h-NTPDase8-IN-1

Modify Date: 2025-11-26 12:50:01

h-NTPDase8-IN-1 Structure
h-NTPDase8-IN-1 structure
Common Name h-NTPDase8-IN-1
CAS Number 716358-51-9 Molecular Weight 275.71
Density N/A Boiling Point N/A
Molecular Formula C10H10ClNO4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of h-NTPDase8-IN-1


h-NTPDase8-IN-1 (compound 2d) is a sulfamoyl-benzamides based and selective inhibitor for h-NTPDases8 (IC50=0.28 μM). h-NTPDases8 is involved in a variety of physiological and pathological functions,such as thrombosis,diabetes,inflammation,and cancer[1].

 Names

Name h-NTPDase8-IN-1

 h-NTPDase8-IN-1 Biological Activity

Description h-NTPDase8-IN-1 (compound 2d) is a sulfamoyl-benzamides based and selective inhibitor for h-NTPDases8 (IC50=0.28 μM). h-NTPDases8 is involved in a variety of physiological and pathological functions,such as thrombosis,diabetes,inflammation,and cancer[1].
Related Catalog
Target

IC50: 0.28 μM for h-NTPDase 8 (a human Nucleoside Triphosphate Diphosphohydrolase)[1]

References

[1]. Zaigham ZH, et al. Synthesis and biological evaluation of sulfamoyl benzamide derivatives as selective inhibitors for h-NTPDases. RSC Adv. 2023 Jul 11;13(30):20909-20915.  

 Chemical & Physical Properties

Molecular Formula C10H10ClNO4S
Molecular Weight 275.71
InChIKey PMRCCCUVEZWWQQ-UHFFFAOYSA-N
SMILES O=C(O)c1cc(S(=O)(=O)NC2CC2)ccc1Cl
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