h-NTPDase8-IN-1

Names

[ Name ]:
h-NTPDase8-IN-1

Biological Activity

[Description]:

h-NTPDase8-IN-1 (compound 2d) is a sulfamoyl-benzamides based and selective inhibitor for h-NTPDases8 (IC50=0.28 μM). h-NTPDases8 is involved in a variety of physiological and pathological functions，such as thrombosis，diabetes，inflammation，and cancer[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase

Research Areas >> Inflammation/Immunology

Research Areas >> Metabolic Disease

[Target]

IC50: 0.28 μM for h-NTPDase 8 (a human Nucleoside Triphosphate Diphosphohydrolase)[1]

[References]

[1]. Zaigham ZH, et al. Synthesis and biological evaluation of sulfamoyl benzamide derivatives as selective inhibitors for h-NTPDases. RSC Adv. 2023 Jul 11;13(30):20909-20915.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₁₀ClNO₄S

[ Molecular Weight ]:
275.71

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.