716358-51-9

716358-51-9 structure

Name: h-NTPDase8-IN-1
Chemical Name: h-NTPDase8-IN-1
CAS Number: 716358-51-9
Molecular Formula: C₁₀H₁₀ClNO₄S
Molecular Weight: 275.71
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphatase
Create Date: 2023-10-11 15:23:18
Modify Date: 2024-01-13 14:14:26
h-NTPDase8-IN-1 (compound 2d) is a sulfamoyl-benzamides based and selective inhibitor for h-NTPDases8 (IC50=0.28 μM). h-NTPDases8 is involved in a variety of physiological and pathological functions，such as thrombosis，diabetes，inflammation，and cancer[1].

Name	h-NTPDase8-IN-1

Description	h-NTPDase8-IN-1 (compound 2d) is a sulfamoyl-benzamides based and selective inhibitor for h-NTPDases8 (IC50=0.28 μM). h-NTPDases8 is involved in a variety of physiological and pathological functions，such as thrombosis，diabetes，inflammation，and cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease
Target	IC50: 0.28 μM for h-NTPDase 8 (a human Nucleoside Triphosphate Diphosphohydrolase)[1]
References	[1]. Zaigham ZH, et al. Synthesis and biological evaluation of sulfamoyl benzamide derivatives as selective inhibitors for h-NTPDases. RSC Adv. 2023 Jul 11;13(30):20909-20915.

Molecular Formula	C₁₀H₁₀ClNO₄S
Molecular Weight	275.71