PIPERMETHYSTINE

Modify Date: 2024-01-10 15:40:50

PIPERMETHYSTINE Structure
PIPERMETHYSTINE structure
Common Name PIPERMETHYSTINE
CAS Number 71627-22-0 Molecular Weight 287.31
Density 1.23g/cm3 Boiling Point 459.9ºC at 760 mmHg
Molecular Formula C16H17NO4 Melting Point N/A
MSDS N/A Flash Point 231.9ºC

 Use of PIPERMETHYSTINE


Pipermethystine is an alkaloid that can be isolated from the Kava plant. Pipermethystine decreases HepG2 cell cellular ATP levels, mitochondrial membrane potential, and induces apoptosis[1].

 Names

Name [6-oxo-1-(3-phenylpropanoyl)-2,3-dihydropyridin-3-yl] acetate
Synonym More Synonyms

 PIPERMETHYSTINE Biological Activity

Description Pipermethystine is an alkaloid that can be isolated from the Kava plant. Pipermethystine decreases HepG2 cell cellular ATP levels, mitochondrial membrane potential, and induces apoptosis[1].
Related Catalog
References

[1]. Nerurkar PV, et al. In vitro toxicity of kava alkaloid, pipermethystine, in HepG2 cells compared to kavalactones. Toxicol Sci. 2004 May;79(1):106-11.  

 Chemical & Physical Properties

Density 1.23g/cm3
Boiling Point 459.9ºC at 760 mmHg
Molecular Formula C16H17NO4
Molecular Weight 287.31
Flash Point 231.9ºC
Exact Mass 287.11600
PSA 63.68000
LogP 1.41380
Index of Refraction 1.574

 Synthetic Route

~98%

PIPERMETHYSTINE Structure

PIPERMETHYSTINE

CAS#:71627-22-0

Literature: Arrayas; Alcudia; Liebeskind Organic letters, 2001 , vol. 3, # 21 p. 3381 - 3383

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PIPERMETHYSTINE Structure

PIPERMETHYSTINE

CAS#:71627-22-0

Literature: Arrayas; Alcudia; Liebeskind Organic letters, 2001 , vol. 3, # 21 p. 3381 - 3383

~%

PIPERMETHYSTINE Structure

PIPERMETHYSTINE

CAS#:71627-22-0

Literature: Arrayas; Alcudia; Liebeskind Organic letters, 2001 , vol. 3, # 21 p. 3381 - 3383

~%

PIPERMETHYSTINE Structure

PIPERMETHYSTINE

CAS#:71627-22-0

Literature: Arrayas; Alcudia; Liebeskind Organic letters, 2001 , vol. 3, # 21 p. 3381 - 3383

~%

PIPERMETHYSTINE Structure

PIPERMETHYSTINE

CAS#:71627-22-0

Literature: Arrayas; Alcudia; Liebeskind Organic letters, 2001 , vol. 3, # 21 p. 3381 - 3383

 Synonyms

(+/-)-5-acetoxy-5,6-dihydro-N-(1-oxo-3-phenylpropyl)-2(1H)-pyridone
Pipermethistin
2(1H)-Pyridinone,5-(acetyloxy)-5,6-dihydro-1-(1-oxo-3-phenylpropyl)
6-Oxo-1-(3-phenylpropanoyl)-1,2,3,6-tetrahydro-3-pyridinyl acetate
(+/-)-pipermethystine
5-acetoxy-1-(3-phenyl-propionyl)-5,6-dihydro-1H-pyridin-2-one