71627-22-0

71627-22-0 structure

Name: PIPERMETHYSTINE
Chemical Name: [6-oxo-1-(3-phenylpropanoyl)-2,3-dihydropyridin-3-yl] acetate
CAS Number: 71627-22-0
Molecular Formula: C₁₆H₁₇NO₄
Molecular Weight: 287.31
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2017-10-19 09:52:32
Modify Date: 2025-08-28 15:15:46
Pipermethystine is an alkaloid that can be isolated from the Kava plant. Pipermethystine decreases HepG2 cell cellular ATP levels, mitochondrial membrane potential, and induces apoptosis[1].

Name	[6-oxo-1-(3-phenylpropanoyl)-2,3-dihydropyridin-3-yl] acetate
Synonyms	(+/-)-5-acetoxy-5,6-dihydro-N-(1-oxo-3-phenylpropyl)-2(1H)-pyridone Pipermethistin 2(1H)-Pyridinone,5-(acetyloxy)-5,6-dihydro-1-(1-oxo-3-phenylpropyl) 6-Oxo-1-(3-phenylpropanoyl)-1,2,3,6-tetrahydro-3-pyridinyl acetate (+/-)-pipermethystine 5-acetoxy-1-(3-phenyl-propionyl)-5,6-dihydro-1H-pyridin-2-one

Description	Pipermethystine is an alkaloid that can be isolated from the Kava plant. Pipermethystine decreases HepG2 cell cellular ATP levels, mitochondrial membrane potential, and induces apoptosis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Nerurkar PV, et al. In vitro toxicity of kava alkaloid, pipermethystine, in HepG2 cells compared to kavalactones. Toxicol Sci. 2004 May;79(1):106-11.

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