1-bromo-2-(2-bromophenyl)disulfanyl-benzene

Modify Date: 2024-01-16 17:25:39

1-bromo-2-(2-bromophenyl)disulfanyl-benzene Structure
1-bromo-2-(2-bromophenyl)disulfanyl-benzene structure
Common Name 1-bromo-2-(2-bromophenyl)disulfanyl-benzene
CAS Number 71112-91-9 Molecular Weight 376.13000
Density 1.83g/cm3 Boiling Point 386.9ºC at 760 mmHg
Molecular Formula C12H8Br2S2 Melting Point N/A
MSDS N/A Flash Point 187.8ºC

 Use of 1-bromo-2-(2-bromophenyl)disulfanyl-benzene


Tubulin inhibitor 28 (compound 2g) is a potent tubulin inhibitor with an IC50 value of 1.2 µM. Tubulin inhibitor 28 shows anti-proliferative activity for MCF-7 cells[1].

 Names

Name 1-bromo-2-[(2-bromophenyl)disulfanyl]benzene
Synonym More Synonyms

  Biological Activity

Description Tubulin inhibitor 28 (compound 2g) is a potent tubulin inhibitor with an IC50 value of 1.2 µM. Tubulin inhibitor 28 shows anti-proliferative activity for MCF-7 cells[1].
Related Catalog
Target

IC50: 1.2 µM (tubulin)[1].

In Vitro Tubulin inhibitor 28 (compound 2g) shows anti-proliferative activity with an IC50 value of >10 µM for MCF-7 cells[1].
References

[1]. Khodyuk RGD, et al. Diaryl disulfides and thiosulfonates as combretastatin A-4 analogues: Synthesis, cytotoxicity and antitubulin activity. Bioorg Chem. 2020 Aug;101:104017.

 Chemical & Physical Properties

Density 1.83g/cm3
Boiling Point 386.9ºC at 760 mmHg
Molecular Formula C12H8Br2S2
Molecular Weight 376.13000
Flash Point 187.8ºC
Exact Mass 373.84300
PSA 50.60000
LogP 6.01100
Index of Refraction 1.745

 Synonyms

1,1'-disulfanediylbis(2-bromobenzene)
di-o-bromophenyl disulfide
1,2-bis(2-bromophenyl)disulfane
bis(2-bromophenyl) disulfide
1,2-bis(2-bromophenyl) disulfide
di-(2-bromophenyl)disulfide
2-bromophenyl disulfide