YUKA1

Modify Date: 2024-01-10 18:33:21

YUKA1 Structure
YUKA1 structure
Common Name YUKA1
CAS Number 708991-09-7 Molecular Weight 292.36
Density N/A Boiling Point N/A
Molecular Formula C13H16N4O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of YUKA1


YUKA1 is a potent and cell permeable Lysine demethylase 5A (KDM5A) inhibitor, with an IC50 of 2.66 μM, less active on KDM5C (IC50, 7.12 μM), and is inactive on KDM5B, KDM6A or KDM6B. YUKA1 increases H3K4me3 levels in human cells with anti-cancer activity[1].

 Names

Name YUKA1

 YUKA1 Biological Activity

Description YUKA1 is a potent and cell permeable Lysine demethylase 5A (KDM5A) inhibitor, with an IC50 of 2.66 μM, less active on KDM5C (IC50, 7.12 μM), and is inactive on KDM5B, KDM6A or KDM6B. YUKA1 increases H3K4me3 levels in human cells with anti-cancer activity[1].
Related Catalog
Target

IC50: 2.66 μM (KDM5A), 7.12 μM (KDM5C)[1]

References

[1]. Gale M, et al. Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance. Oncotarget. 2016 Jun 28;7(26):39931-39944.

 Chemical & Physical Properties

Molecular Formula C13H16N4O2S
Molecular Weight 292.36
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: YUKA1
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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