2,4-dichloro-1-(4-chlorophenyl)benzene

Modify Date: 2025-08-26 10:42:50

2,4-dichloro-1-(4-chlorophenyl)benzene Structure
2,4-dichloro-1-(4-chlorophenyl)benzene structure
 Common Name 2,4-dichloro-1-(4-chlorophenyl)benzene
CAS Number 7012-37-5 Molecular Weight 257.54300
Density 1.351g/cm3 Boiling Point 330.3ºC at 760 mmHg
Molecular Formula C12H7Cl3 Melting Point 206-207℃
MSDS Chinese USA Flash Point 100ºC
Symbol GHS02 GHS07 GHS08 GHS09
GHS02, GHS07, GHS08, GHS09		 Signal Word Danger

 Names

Name 2,4,4'-Trichlorobiphenyl
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.351g/cm3
Boiling Point 330.3ºC at 760 mmHg
Melting Point 206-207℃
Molecular Formula C12H7Cl3
Molecular Weight 257.54300
Flash Point 100ºC
Exact Mass 255.96100
LogP 5.31380
Index of Refraction 1.603
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DV8840000
CHEMICAL NAME :
1,1'-Biphenyl, 2,4,4'-trichloro-
CAS REGISTRY NUMBER :
7012-37-5
BEILSTEIN REFERENCE NO. :
1956846
LAST UPDATED :
199710
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C12-H7-Cl3
MOLECULAR WEIGHT :
257.54

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
273 mg/kg/13W-C
TOXIC EFFECTS :
Liver - other changes Kidney, Ureter, Bladder - other changes in urine composition Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)
REFERENCE :
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 49,301,1996
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
150 mg/kg/3D-I
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other hydrolases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 33,94,1975 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
224 mg/kg
SEX/DURATION :
female 10-16 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
REFERENCE :
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 68,311,1993
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
224 mg/kg
SEX/DURATION :
female 10-16 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - behavioral
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 26,117,1995

 Safety Information

Symbol GHS02 GHS07 GHS08 GHS09
GHS02, GHS07, GHS08, GHS09
Signal Word Danger
Hazard Statements H225-H304-H315-H336-H373-H410
Precautionary Statements P210-P260-P301 + P310-P331-P370 + P378-P403 + P235
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes N,Xn,F
Risk Phrases 33-50/53-11
Safety Phrases 35-60-61-62-33-29-16
RIDADR UN 2315
RTECS DV8840000
Packaging Group II
Hazard Class 9

 Articles27

More Articles
Fish intake and breastfeeding time are associated with serum concentrations of organochlorines in a Swedish population.

Environ. Int. 51 , 88-96, (2013)

Persistent organic pollutants (POPs) exert harmful effects on cognitive, endocrine and immune functions and bioaccumulate in the environment and human tissues. The aim of this study was to investigate...

Vertical distributions of organochlorine pesticides and polychlorinated biphenyls in an agricultural soil core from the Guanzhong Basin, China.

Environ. Monit. Assess. 187(1) , 4159, (2015)

The concentrations and distributions of hexachlorocyclohexanes (HCHs), dichlorodiphenyltrichloroethanes (DDTs), and polychlorinated biphenyls (PCBs) in an agricultural soil core in the Guanzhong Basin...

Suppression of aromatase activity in vitro by PCBs 28 and 105 and Aroclor 1221.

Toxicol. Lett. 152(1) , 91-100, (2004)

The effects of polychlorinated biphenyls (PCBs) on human cytochrome P450 aromatase activity in vitro were investigated using a commercially available microsomal fraction obtained from baculovirus infe...

 Synonyms

2,4-dichloro-1-(4-chlorophenyl)benzene
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