Swertiajaponin structure
|
Common Name | Swertiajaponin | ||
|---|---|---|---|---|
| CAS Number | 6980-25-2 | Molecular Weight | 462.404 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 761.3±60.0 °C at 760 mmHg | |
| Molecular Formula | C22H22O11 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 266.6±26.4 °C | |
Use of SwertiajaponinSwertiajaponin is a tyrosinase inhibitor, forms multiple hydrogen bonds and hydrophobic interactions with the binding pocket of tyrosinase, with an IC50 of 43.47 μM. Swertiajaponin also inhibits oxidative stress-mediated MAPK/MITF signaling, leading to decrease in tyrosinase protein level. Swertiajaponin suppresses melanin accumulation and exhibits strong anti-oxidative activity[1]. |
| Name | swertiajaponin |
|---|---|
| Synonym | More Synonyms |
| Description | Swertiajaponin is a tyrosinase inhibitor, forms multiple hydrogen bonds and hydrophobic interactions with the binding pocket of tyrosinase, with an IC50 of 43.47 μM. Swertiajaponin also inhibits oxidative stress-mediated MAPK/MITF signaling, leading to decrease in tyrosinase protein level. Swertiajaponin suppresses melanin accumulation and exhibits strong anti-oxidative activity[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 43.47 μM (tyrosinase)[1] |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 761.3±60.0 °C at 760 mmHg |
| Molecular Formula | C22H22O11 |
| Molecular Weight | 462.404 |
| Flash Point | 266.6±26.4 °C |
| Exact Mass | 462.116211 |
| PSA | 190.28000 |
| LogP | 1.83 |
| Vapour Pressure | 0.0±2.7 mmHg at 25°C |
| Index of Refraction | 1.717 |
| InChIKey | DLVLXOYLQKCAME-DGHBBABESA-N |
| SMILES | COc1cc2oc(-c3ccc(O)c(O)c3)cc(=O)c2c(O)c1C1OC(CO)C(O)C(O)C1O |
| Storage condition | 2-8℃ |
| Swertiajaponin |
| D-Glucitol, 1,5-anhydro-1-C-[2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-6-yl]-, (1S)- |
| (1S)-1,5-Anhydro-1-[2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-4-oxo-4H-chromen-6-yl]-D-glucitol |
| Leucanthoside |
| 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one |