Name | swertiajaponin |
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Synonyms |
Swertiajaponin
D-Glucitol, 1,5-anhydro-1-C-[2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-6-yl]-, (1S)- (1S)-1,5-Anhydro-1-[2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-4-oxo-4H-chromen-6-yl]-D-glucitol Leucanthoside 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one |
Description | Swertiajaponin is a tyrosinase inhibitor, forms multiple hydrogen bonds and hydrophobic interactions with the binding pocket of tyrosinase, with an IC50 of 43.47 μM. Swertiajaponin also inhibits oxidative stress-mediated MAPK/MITF signaling, leading to decrease in tyrosinase protein level. Swertiajaponin suppresses melanin accumulation and exhibits strong anti-oxidative activity[1]. |
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Related Catalog | |
Target |
IC50: 43.47 μM (tyrosinase)[1] |
References |
Density | 1.6±0.1 g/cm3 |
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Boiling Point | 761.3±60.0 °C at 760 mmHg |
Molecular Formula | C22H22O11 |
Molecular Weight | 462.404 |
Flash Point | 266.6±26.4 °C |
Exact Mass | 462.116211 |
PSA | 190.28000 |
LogP | 1.83 |
Vapour Pressure | 0.0±2.7 mmHg at 25°C |
Index of Refraction | 1.717 |
Storage condition | 2-8℃ |