Succinaldehydic acid

Modify Date: 2024-01-06 10:57:00

Succinaldehydic acid structure	Common Name	Succinaldehydic acid
	CAS Number	692-29-5	Molecular Weight	102.089
	Density	1.2±0.1 g/cm3	Boiling Point	248.6±23.0 °C at 760 mmHg
	Molecular Formula	C₄H₆O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	118.4±19.1 °C

Use of Succinaldehydic acid

Succinaldehydic acid is a catabolite of GABA.

Name	succinic semialdehyde
Synonym	More Synonyms

Description	Succinaldehydic acid is a catabolite of GABA.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others
In Vitro	Succinaldehydic acid (Succinic semialdehyde) is a catabolite of GABA, which is catabolized in the mitochondrial matrix through the GABA shunt, encompassing transamination to Succinaldehydic acid followed by oxidation to succinate by the concerted actions of GABA transaminase (GABA-T) and succinic semialdehyde dehydrogenase (SSADH), respectively[1].
References	[1]. Ravasz D, et al. Catabolism of GABA, succinic semialdehyde or gamma-hydroxybutyrate through the GABA shunt impair mitochondrial substrate-level phosphorylation. Neurochem Int. 2017 Oct;109:41-53.

Density	1.2±0.1 g/cm3
Boiling Point	248.6±23.0 °C at 760 mmHg
Molecular Formula	C₄H₆O₃
Molecular Weight	102.089
Flash Point	118.4±19.1 °C
Exact Mass	102.031693
PSA	54.37000
LogP	-0.35
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.430

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WM3380000

CHEMICAL NAME :: Succinaldehydic acid

CAS REGISTRY NUMBER :: 692-29-5

BEILSTEIN REFERENCE NO. :: 1745187

LAST UPDATED :: 199712

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C4-H6-O3

MOLECULAR WEIGHT :: 102.10

WISWESSER LINE NOTATION :: VH2VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMXXAJ French Medicament Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Discontinued. Volume(issue)/page/year: #3296M

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1900 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 3,697,1969

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMXXAJ French Medicament Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Discontinued. Volume(issue)/page/year: #3296M

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMXXAJ French Medicament Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Discontinued. Volume(issue)/page/year: #3296M

HS Code	2918300090

Precursor 9
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DownStream 10
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HS Code	2918300090
Summary	2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

MFCD00010579

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4-Oxobutyric acid

Succinic semialdehyde

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Succinic semialdehyde monomer

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