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692-29-5

692-29-5 structure
692-29-5 structure
  • Name: Succinaldehydic acid
  • Chemical Name: succinic semialdehyde
  • CAS Number: 692-29-5
  • Molecular Formula: C4H6O3
  • Molecular Weight: 102.089
  • Catalog: Research Areas Others
  • Create Date: 2018-09-03 21:54:34
  • Modify Date: 2024-01-06 10:57:00
  • Succinaldehydic acid is a catabolite of GABA.

Name succinic semialdehyde
Synonyms MFCD00010579
3-Formylpropanoic acid
Succinic acid semialdehyde
Butanoic acid, 4-oxo-
4-Oxobutanoic acid
3-Formylpropionic acid
Butryaldehydic acid
4-Oxobutyric acid
Succinic semialdehyde
Succinaldehydic acid
Succinic semialdehyde monomer
Description Succinaldehydic acid is a catabolite of GABA.
Related Catalog
In Vitro Succinaldehydic acid (Succinic semialdehyde) is a catabolite of GABA, which is catabolized in the mitochondrial matrix through the GABA shunt, encompassing transamination to Succinaldehydic acid followed by oxidation to succinate by the concerted actions of GABA transaminase (GABA-T) and succinic semialdehyde dehydrogenase (SSADH), respectively[1].
References

[1]. Ravasz D, et al. Catabolism of GABA, succinic semialdehyde or gamma-hydroxybutyrate through the GABA shunt impair mitochondrial substrate-level phosphorylation. Neurochem Int. 2017 Oct;109:41-53.

Density 1.2±0.1 g/cm3
Boiling Point 248.6±23.0 °C at 760 mmHg
Molecular Formula C4H6O3
Molecular Weight 102.089
Flash Point 118.4±19.1 °C
Exact Mass 102.031693
PSA 54.37000
LogP -0.35
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.430

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WM3380000
CHEMICAL NAME :
Succinaldehydic acid
CAS REGISTRY NUMBER :
692-29-5
BEILSTEIN REFERENCE NO. :
1745187
LAST UPDATED :
199712
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C4-H6-O3
MOLECULAR WEIGHT :
102.10
WISWESSER LINE NOTATION :
VH2VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMXXAJ French Medicament Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Discontinued. Volume(issue)/page/year: #3296M
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1900 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 3,697,1969
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMXXAJ French Medicament Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Discontinued. Volume(issue)/page/year: #3296M
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMXXAJ French Medicament Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Discontinued. Volume(issue)/page/year: #3296M
HS Code 2918300090
HS Code 2918300090
Summary 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%