(+/-)-Pinocembrin

Modify Date: 2024-01-08 19:20:43

(+/-)-Pinocembrin Structure
(+/-)-Pinocembrin structure
Common Name (+/-)-Pinocembrin
CAS Number 68745-38-0 Molecular Weight 256.25300
Density 1.386g/cm3 Boiling Point 520.6ºC at 760 mmHg
Molecular Formula C15H12O4 Melting Point 202-203ºC
MSDS Chinese Flash Point 203.3ºC

 Use of (+/-)-Pinocembrin


(±)-Pinocembrin ((±)-5,7-Dihydroxyflavanone) is a GPR120 ligand able to promote wound healing in HaCaT cell line[1].

 Names

Name 5,7-dihydroxy-2-phenyl-2,3-dihydrochromen-4-one
Synonym More Synonyms

 (+/-)-Pinocembrin Biological Activity

Description (±)-Pinocembrin ((±)-5,7-Dihydroxyflavanone) is a GPR120 ligand able to promote wound healing in HaCaT cell line[1].
Related Catalog
In Vitro (±)-Pinocembrin shows wound-healing effect (EC50=0.07 µM), probably involves other mechanisms besides GPR120 activation[1].
References

[1]. Mazzotta S, et al. Pinocembrin and its linolenoyl ester derivative induce wound healing activity in HaCaT cell line potentially involving a GPR120/FFA4 mediated pathway. Bioorg Chem. 2021;108:104657.

 Chemical & Physical Properties

Density 1.386g/cm3
Boiling Point 520.6ºC at 760 mmHg
Melting Point 202-203ºC
Molecular Formula C15H12O4
Molecular Weight 256.25300
Flash Point 203.3ºC
Exact Mass 256.07400
PSA 66.76000
LogP 2.80430
Vapour Pressure 1.85E-11mmHg at 25°C
Index of Refraction 1.661
Storage condition 2-8°C

 Synonyms

(2S)-5,7-dihydroxyflavanone
(2S)-2,3-dihydro-5,7-dihydroxy-2-phenyl-4H-1-benzopyran-4-one
(2S)-pinocembrin
dihydrochrysin
pinocembrin
5,7-Dihydroxyflavanone
Galangin flavanone
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