RR-11a analog

Modify Date: 2024-02-04 11:33:06

RR-11a analog Structure
RR-11a analog structure
Common Name RR-11a analog
CAS Number 685543-66-2 Molecular Weight 491.49
Density N/A Boiling Point N/A
Molecular Formula C22H29N5O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RR-11a analog


RR-11a analog is a potent and selective inhibitors of asparaginyl endopeptidases (AE) (Legumain), with IC50 values of 4.5 nM, 4.5 nM and 31 nM for AE1 in Trichomonas Vaginalis, AE in Ixodes ricinus and AE in Schistosoma mansoni, respectively[1].

 Names

Name RR-11a analog

 RR-11a analog Biological Activity

Description RR-11a analog is a potent and selective inhibitors of asparaginyl endopeptidases (AE) (Legumain), with IC50 values of 4.5 nM, 4.5 nM and 31 nM for AE1 in Trichomonas Vaginalis, AE in Ixodes ricinus and AE in Schistosoma mansoni, respectively[1].
Related Catalog
Target

IC50: 4.5 nM (AE1 in Trichomonas Vaginalis), 4.5 nM (AE in Ixodes ricinus), 31 nM (AE in Schistosoma mansoni)[1].

References

[1]. Götz MG, et al. Aza-peptidyl Michael acceptors. A new class of potent and selective inhibitors of asparaginyl endopeptidases (legumains) from evolutionarily diverse pathogens. J Med Chem. 2008 May 8;51(9):2816-32.

 Chemical & Physical Properties

Molecular Formula C22H29N5O8
Molecular Weight 491.49
Storage condition 2-8℃