AP-C3

Modify Date: 2024-01-21 10:06:20

AP-C3 Structure
AP-C3 structure
Common Name AP-C3
CAS Number 682795-78-4 Molecular Weight 393.44
Density N/A Boiling Point N/A
Molecular Formula C22H23N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AP-C3


AP-C3 is a potent inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 6.3. AP-C3 only weakly inhibits cGKII-dependent anion secretion[1].

 Names

Name AP-C3

 AP-C3 Biological Activity

Description AP-C3 is a potent inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 6.3. AP-C3 only weakly inhibits cGKII-dependent anion secretion[1].
Related Catalog
Target

pIC50: 6.5 (cGKII)[1]

References

[1]. Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293(21):8173-8181.  

 Chemical & Physical Properties

Molecular Formula C22H23N3O4
Molecular Weight 393.44
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