Trifolirhizin

Modify Date: 2025-08-23 18:41:13

Trifolirhizin Structure
Trifolirhizin structure
 Common Name Trifolirhizin
CAS Number 6807-83-6 Molecular Weight 446.404
Density 1.6±0.1 g/cm3 Boiling Point 658.7±55.0 °C at 760 mmHg
Molecular Formula C22H22O10 Melting Point 142-144ºC
MSDS Chinese USA Flash Point 352.2±31.5 °C
Symbol GHS09
GHS09		 Signal Word Warning

 Use of Trifolirhizin


Trifolirhizin is a pterocarpan flavonoid isolated from the roots of Sophora flavescens. Trifolirhizin possesses potent tyrosinase inhibitory activity with an IC50 of 506 μM[1]. Trifolirhizin exhibits potential anti-inflammatory and anticancer activities[2].

 Names

Name Trifolirhizin
Synonym More Synonyms

 Trifolirhizin Biological Activity

Description Trifolirhizin is a pterocarpan flavonoid isolated from the roots of Sophora flavescens. Trifolirhizin possesses potent tyrosinase inhibitory activity with an IC50 of 506 μM[1]. Trifolirhizin exhibits potential anti-inflammatory and anticancer activities[2].
Related Catalog
Target

IC50: 506 μM (tyrosinase)[1]

References

[1]. Hyun SK, et al. Inhibitory effects of kurarinol, kuraridinol, and trifolirhizin from Sophora flavescens on tyrosinase and melanin synthesis. Biol Pharm Bull. 2008 Jan;31(1):154-8.

[2]. Zhou H, et al. Anti-Inflammatory and antiproliferative activities of trifolirhizin, a flavonoid from Sophora flavescens roots. J Agric Food Chem. 2009 Jun 10;57(11):4580-5.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 658.7±55.0 °C at 760 mmHg
Melting Point 142-144ºC
Molecular Formula C22H22O10
Molecular Weight 446.404
Flash Point 352.2±31.5 °C
Exact Mass 446.121307
PSA 136.30000
LogP 0.75
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.681
Storage condition ?20°C

 Safety Information

Symbol GHS09
GHS09
Signal Word Warning
Hazard Statements H410
Precautionary Statements P273-P501
Hazard Codes N
Risk Phrases 50
Safety Phrases 61-24/25
RIDADR UN 3077 9 / PGIII
HS Code 29389090

 Synonyms

(6aR,12aR)-6a,12a-Dihydro-6H-[1,3]dioxolo[5,6][1]benzofuro[3,2-c]chromen-3-yl β-D-glucopyranoside
β-D-Glucopyranoside, (6aR,12aR)-6a,12a-dihydro-6H-[1,3]dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-3-yl
n1959
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