6807-83-6

6807-83-6 structure

Name: Trifolirhizin
Chemical Name: Trifolirhizin
CAS Number: 6807-83-6
Molecular Formula: C₂₂H₂₂O₁₀
Molecular Weight: 446.404
Catalog: Natural product Phenols
Create Date: 2018-03-15 08:00:00
Modify Date: 2025-08-23 18:41:13
Trifolirhizin is a pterocarpan flavonoid isolated from the roots of Sophora flavescens. Trifolirhizin possesses potent tyrosinase inhibitory activity with an IC50 of 506 μM[1]. Trifolirhizin exhibits potential anti-inflammatory and anticancer activities[2].

Name	Trifolirhizin
Synonyms	(6aR,12aR)-6a,12a-Dihydro-6H-[1,3]dioxolo[5,6][1]benzofuro[3,2-c]chromen-3-yl β-D-glucopyranoside β-D-Glucopyranoside, (6aR,12aR)-6a,12a-dihydro-6H-[1,3]dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-3-yl n1959

Description	Trifolirhizin is a pterocarpan flavonoid isolated from the roots of Sophora flavescens. Trifolirhizin possesses potent tyrosinase inhibitory activity with an IC50 of 506 μM[1]. Trifolirhizin exhibits potential anti-inflammatory and anticancer activities[2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase
Target	IC50: 506 μM (tyrosinase)[1]
References	[1]. Hyun SK, et al. Inhibitory effects of kurarinol, kuraridinol, and trifolirhizin from Sophora flavescens on tyrosinase and melanin synthesis. Biol Pharm Bull. 2008 Jan;31(1):154-8. [2]. Zhou H, et al. Anti-Inflammatory and antiproliferative activities of trifolirhizin, a flavonoid from Sophora flavescens roots. J Agric Food Chem. 2009 Jun 10;57(11):4580-5.