PEG13

Modify Date: 2024-01-04 20:44:33

PEG13 Structure
PEG13 structure
Common Name PEG13
CAS Number 6790-09-6 Molecular Weight 546.646
Density 1.1±0.1 g/cm3 Boiling Point 602.0±50.0 °C at 760 mmHg
Molecular Formula C24H50O13 Melting Point 38ºC
MSDS N/A Flash Point 317.9±30.1 °C

 Use of PEG13


Dodecaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name dodecaethylene glycol
Synonym More Synonyms

 PEG13 Biological Activity

Description Dodecaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 602.0±50.0 °C at 760 mmHg
Melting Point 38ºC
Molecular Formula C24H50O13
Molecular Weight 546.646
Flash Point 317.9±30.1 °C
Exact Mass 546.325134
PSA 141.99000
LogP -5.09
Vapour Pressure 0.0±3.9 mmHg at 25°C
Index of Refraction 1.466

 Safety Information

Hazard Codes Xi
HS Code 2909499000

 Synthetic Route

 Customs

HS Code 2909499000
Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

 Synonyms

PEG13
2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
MFCD06201001
3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane-1,35-diol (9CI)
EINECS 229-859-1
Dodecaethylene Glycol
PEG-13
3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane-1,35-diol
dodecaethyleneglycol
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