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PEG13

Names

[ CAS No. ]:
6790-09-6

[ Name ]:
PEG13

[Synonym ]:
PEG13
2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
MFCD06201001
3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane-1,35-diol (9CI)
EINECS 229-859-1
Dodecaethylene Glycol
PEG-13
3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane-1,35-diol
dodecaethyleneglycol

Biological Activity

[Description]:

Dodecaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
602.0±50.0 °C at 760 mmHg

[ Melting Point ]:
38ºC

[ Molecular Formula ]:
C24H50O13

[ Molecular Weight ]:
546.646

[ Flash Point ]:
317.9±30.1 °C

[ Exact Mass ]:
546.325134

[ PSA ]:
141.99000

[ LogP ]:
-5.09

[ Vapour Pressure ]:
0.0±3.9 mmHg at 25°C

[ Index of Refraction ]:
1.466

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2909499000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2909499000

[ Summary ]:
2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

Related Compounds

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