Tosylate of Tetraethylene glycol monobenzyl ether

Names

[ Name ]:
Tosylate of Tetraethylene glycol monobenzyl ether

[Synonym ]:
tetraethylene glycol monobenzyl ether tosylate
13-phenyl-3,6,9,12-tetraoxatridecan-1-yl p-toluenesulfonate
2,5,8,11-Tetraoxatridecan-13-ol,1-phenyl-,4-methylbenzenesulfonate
1-phenyl-2,5,8,11-tetraoxatridecan-13-yl 4-methylbenzenesulfonate
Tosylate of Tetraethylene glycol monobenzyl ether

Biological Activity

[Description]:

Benzyl-PEG4-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₃₂O₈S

[ Molecular Weight ]:
456.55000

[ Exact Mass ]:
456.18200

[ PSA ]:
119.90000

[ LogP ]:
3.56780

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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