Mcl-1-Puma inhibitor 8
Modify Date: 2025-08-24 08:09:59
Mcl-1-Puma inhibitor 8 structure
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Common Name | Mcl-1-Puma inhibitor 8 | ||
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| CAS Number | 678158-55-9 | Molecular Weight | 393.50 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H23N3O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Mcl-1-Puma inhibitor 8Mcl1-IN-8 (Comp8) is a Mcl-1-PUMA interface inhibitor, with a Ki of 0.3 μM. Mcl1-IN-8 (Comp8) exhibits dual activity on reduce PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis in cancer cells[1]. |
| Name | Mcl1-IN-8 |
|---|
| Description | Mcl1-IN-8 (Comp8) is a Mcl-1-PUMA interface inhibitor, with a Ki of 0.3 μM. Mcl1-IN-8 (Comp8) exhibits dual activity on reduce PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis in cancer cells[1]. |
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| Related Catalog | |
| Target |
Mcl-1:0.3 μM (Ki) |
| References |
| Molecular Formula | C22H23N3O2S |
|---|---|
| Molecular Weight | 393.50 |
| InChIKey | IBEWMFVUBLAYJT-SILNSSARSA-N |
| SMILES | O=C1N=C(N2CCN(CCO)CC2)SC1=Cc1ccc(-c2ccccc2)cc1 |