(E)-Mcl-1 inhibitor 7

Modify Date: 2025-09-12 18:46:45

(E)-Mcl-1 inhibitor 7 Structure
(E)-Mcl-1 inhibitor 7 structure
Common Name (E)-Mcl-1 inhibitor 7
CAS Number 2417463-86-4 Molecular Weight 672.23
Density N/A Boiling Point N/A
Molecular Formula C34H42ClN3O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (E)-Mcl-1 inhibitor 7


(E)-Mcl-1 inhibitor 7 (Example 34) is a Mcl-1 inhibitor (Ki: <1 nM, IC50: <500 nM). (E)-Mcl-1 inhibitor 7 can be used for research of cancers[1].

 Names

Name (E)-Mcl-1 inhibitor 7

 (E)-Mcl-1 inhibitor 7 Biological Activity

Description (E)-Mcl-1 inhibitor 7 (Example 34) is a Mcl-1 inhibitor (Ki: <1 nM, IC50: <500 nM). (E)-Mcl-1 inhibitor 7 can be used for research of cancers[1].
Related Catalog
Target

Mcl-1:<10 nM (Ki)

Mcl-1:<500 nM (IC50)

References

[1]. Zhuo, Jincong, et al. Preparation of spiro-sulfonamide derivatives as inhibitors of myeloid cell leukemia-1 (MCL-1) protein for the treatment of cancer. Patent. WO2020097577.

 Chemical & Physical Properties

Molecular Formula C34H42ClN3O7S
Molecular Weight 672.23
InChIKey BBDMFVGCKZAPPY-VHSMYAGPSA-N
SMILES CN(C)C(=O)OC1C=CCOC(C)(C)C(=O)NS(=O)(=O)c2ccc3c(c2)N(CC2CCC21)CC1(CCCc2cc(Cl)ccc21)CO3
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