Dihydromunduletone
Modify Date: 2025-08-27 15:46:31
Dihydromunduletone structure
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Common Name | Dihydromunduletone | ||
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| CAS Number | 674786-20-0 | Molecular Weight | 424.493 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H28O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DihydromunduletoneDihydromunduletone is a rotenoid derivative that selectively inhibits GPR56 (IC50=21 uM) and GPR114/ADGRG5, but not GPR110 or Class A GPCRs; maximally inhibits GPR56 at 50 uM, also dramatically inhibits GPR114 7TM–stimulated Gs activity; also inhibit the growth of the zebrafish intersegmental vessels. |
| Name | Dihydromunduletone |
|---|
| Description | Dihydromunduletone is a rotenoid derivative that selectively inhibits GPR56 (IC50=21 uM) and GPR114/ADGRG5, but not GPR110 or Class A GPCRs; maximally inhibits GPR56 at 50 uM, also dramatically inhibits GPR114 7TM–stimulated Gs activity; also inhibit the growth of the zebrafish intersegmental vessels. |
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| References | References 1. Stoveken HM, et al. Mol Pharmacol. 2016 Sep;90(3):214-24. 2. Wang C, et al. Eur Urol. 2010 Sep;58(3):418-26. View Related Products by Target Other Targets |
| Molecular Formula | C25H28O6 |
|---|---|
| Molecular Weight | 424.493 |
| InChIKey | RMVZECFNOTWEKD-UHFFFAOYSA-N |
| SMILES | COc1c(CC(=O)c2cc3c(cc2O)OC(C)(C)C(O)C3)ccc2c1C=CC(C)(C)O2 |