674786-20-0
674786-20-0 structure
- Name: Dihydromunduletone
- Chemical Name: Dihydromunduletone
- CAS Number: 674786-20-0
- Molecular Formula: C25H28O6
- Molecular Weight: 424.493
- Catalog: Research Areas Cancer
- Create Date: 2020-01-20 16:21:56
- Modify Date: 2025-08-27 15:46:31
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Dihydromunduletone is a rotenoid derivative that selectively inhibits GPR56 (IC50=21 uM) and GPR114/ADGRG5, but not GPR110 or Class A GPCRs; maximally inhibits GPR56 at 50 uM, also dramatically inhibits GPR114 7TM–stimulated Gs activity; also inhibit the growth of the zebrafish intersegmental vessels.
| Name | Dihydromunduletone |
|---|
| Description | Dihydromunduletone is a rotenoid derivative that selectively inhibits GPR56 (IC50=21 uM) and GPR114/ADGRG5, but not GPR110 or Class A GPCRs; maximally inhibits GPR56 at 50 uM, also dramatically inhibits GPR114 7TM–stimulated Gs activity; also inhibit the growth of the zebrafish intersegmental vessels. |
|---|---|
| References | References 1. Stoveken HM, et al. Mol Pharmacol. 2016 Sep;90(3):214-24. 2. Wang C, et al. Eur Urol. 2010 Sep;58(3):418-26. View Related Products by Target Other Targets |
| Molecular Formula | C25H28O6 |
|---|---|
| Molecular Weight | 424.493 |