Rasarfin
Modify Date: 2025-08-26 12:06:07
Rasarfin structure
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Common Name | Rasarfin | ||
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| CAS Number | 674359-73-0 | Molecular Weight | 425.91 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H24ClN3O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of RasarfinRasarfin is a dual Ras and ARF6 inhibitor[1]. |
| Name | Rasarfin |
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| Description | Rasarfin is a dual Ras and ARF6 inhibitor[1]. |
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| Related Catalog | |
| In Vitro | Rasarfin also potently inhibits agonist-induced ERK1/2 signaling by GPCRs, and MAPK and Akt signaling by EGFR, as well as prevents cancer cell proliferation[1]. Rasarfin blocks GPCR internalization through inhibition of ARF6[1]. Rasarfin treatment results in a dose-dependent reduction in MDA-MB-231 cells[1]. Rasarfin inhibits the recruitment of the clathrin adaptor AP-2 to β-arrestin2 and receptor internalization, both processes that require active ARF6[1]. |
| References |
| Molecular Formula | C23H24ClN3O3 |
|---|---|
| Molecular Weight | 425.91 |
| InChIKey | SRZCCUYFJZQLGE-UHFFFAOYSA-N |
| SMILES | CC(C)C(=O)N1CCN(c2ccc(NC(=O)c3cc4ccccc4o3)cc2Cl)CC1 |
| Hazard Codes | Xi |
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