Dehydronifedipine

Modify Date: 2024-01-08 15:25:48

Dehydronifedipine Structure
Dehydronifedipine structure
Common Name Dehydronifedipine
CAS Number 67035-22-7 Molecular Weight 344.31900
Density 1.284g/cm3 Boiling Point 443.7ºC at 760 mmHg
Molecular Formula C17H16N2O6 Melting Point 100-105ºC
MSDS Chinese USA Flash Point 222.1ºC
Symbol GHS05
GHS05
Signal Word Danger

 Names

Name 2,6-Dimethyl-4-(2'-nitrophenyl)-3,5-pyridinecarboxylic acid dimethyl ester, Oxidized Nifedipine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.284g/cm3
Boiling Point 443.7ºC at 760 mmHg
Melting Point 100-105ºC
Molecular Formula C17H16N2O6
Molecular Weight 344.31900
Flash Point 222.1ºC
Exact Mass 344.10100
PSA 111.31000
LogP 3.37000
Appearance of Characters powder | yellow
Index of Refraction 1.575
Storage condition 2-8°C

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H318
Precautionary Statements P280-P305 + P351 + P338 + P310
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases 41
Safety Phrases 26-39
RIDADR NONH for all modes of transport
WGK Germany 2

 Synthetic Route

~97%

Dehydronifedipine Structure

Dehydronifedipine

CAS#:67035-22-7

Literature: Filipan-Litvic, Mirela; Litvic, Mladen; Vinkovic, Vladimir Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 20 p. 9276 - 9282

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Dehydronifedipine Structure

Dehydronifedipine

CAS#:67035-22-7

Literature: Biochemical Pharmacology, , vol. 65, # 8 p. 1215 - 1226

~%

Dehydronifedipine Structure

Dehydronifedipine

CAS#:67035-22-7

Literature: Biochemical Pharmacology, , vol. 65, # 8 p. 1215 - 1226

~5%

Dehydronifedipine Structure

Dehydronifedipine

CAS#:67035-22-7

Literature: Journal of the Indian Chemical Society, , vol. 68, # 4 p. 237 - 239

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Dehydronifedipine Structure

Dehydronifedipine

CAS#:67035-22-7

Literature: Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, , vol. 29, # 3 p. 277 - 279

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Dehydronifedipine Structure

Dehydronifedipine

CAS#:67035-22-7

Literature: Central European Journal of Chemistry, , vol. 8, # 4 p. 744 - 749

 Articles11

More Articles
Nuclear translocation of nuclear transcription factor-kappa B by alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors leads to transcription of p53 and cell death in dopaminergic neurons.

Mol. Pharmacol. 63(4) , 784-90, (2003)

We describe a new molecular mechanism of cell death by excitotoxicity mediated through nuclear transcription factor kappa B (NF kappa B) in rat embryonic cultures of dopaminergic neurons. Treatment of...

Enhancement of CYP3A4 activity in Hep G2 cells by lentiviral transfection of hepatocyte nuclear factor-1 alpha.

PLoS ONE 9(4) , e94885, (2014)

Human hepatoma cell lines are commonly used as alternatives to primary hepatocytes for the study of drug metabolism in vitro. However, the phase I cytochrome P450 (CYP) enzyme activities in these cell...

Interactions of endosulfan and methoxychlor involving CYP3A4 and CYP2B6 in human HepaRG cells.

Drug Metab. Dispos. 42(8) , 1235-40, (2014)

Humans are usually exposed to several pesticides simultaneously; consequently, combined actions between pesticides themselves or between pesticides and other chemicals need to be addressed in the risk...

 Synonyms

dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate
Dehydronifedipine
B 4759
Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate
Nifedipine Impurity 1
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