Dehydronifedipine structure
|
Common Name | Dehydronifedipine | ||
|---|---|---|---|---|
| CAS Number | 67035-22-7 | Molecular Weight | 344.31900 | |
| Density | 1.284g/cm3 | Boiling Point | 443.7ºC at 760 mmHg | |
| Molecular Formula | C17H16N2O6 | Melting Point | 100-105ºC | |
| MSDS | Chinese USA | Flash Point | 222.1ºC | |
| Symbol |
GHS05 |
Signal Word | Danger | |
| Name | 2,6-Dimethyl-4-(2'-nitrophenyl)-3,5-pyridinecarboxylic acid dimethyl ester, Oxidized Nifedipine |
|---|---|
| Synonym | More Synonyms |
| Density | 1.284g/cm3 |
|---|---|
| Boiling Point | 443.7ºC at 760 mmHg |
| Melting Point | 100-105ºC |
| Molecular Formula | C17H16N2O6 |
| Molecular Weight | 344.31900 |
| Flash Point | 222.1ºC |
| Exact Mass | 344.10100 |
| PSA | 111.31000 |
| LogP | 3.37000 |
| Appearance of Characters | powder | yellow |
| Index of Refraction | 1.575 |
| InChIKey | UMQHJQGNGLQJPF-UHFFFAOYSA-N |
| SMILES | COC(=O)c1c(C)nc(C)c(C(=O)OC)c1-c1ccccc1[N+](=O)[O-] |
| Storage condition | 2-8°C |
|
~97%
Dehydronifedipine CAS#:67035-22-7 |
| Literature: Filipan-Litvic, Mirela; Litvic, Mladen; Vinkovic, Vladimir Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 20 p. 9276 - 9282 |
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~%
Dehydronifedipine CAS#:67035-22-7 |
| Literature: Biochemical Pharmacology, , vol. 65, # 8 p. 1215 - 1226 |
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~%
Dehydronifedipine CAS#:67035-22-7 |
| Literature: Biochemical Pharmacology, , vol. 65, # 8 p. 1215 - 1226 |
|
~5%
Dehydronifedipine CAS#:67035-22-7 |
| Literature: Journal of the Indian Chemical Society, , vol. 68, # 4 p. 237 - 239 |
|
~%
Dehydronifedipine CAS#:67035-22-7 |
| Literature: Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, , vol. 29, # 3 p. 277 - 279 |
|
~%
Dehydronifedipine CAS#:67035-22-7 |
| Literature: Central European Journal of Chemistry, , vol. 8, # 4 p. 744 - 749 |
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Nuclear translocation of nuclear transcription factor-kappa B by alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors leads to transcription of p53 and cell death in dopaminergic neurons.
Mol. Pharmacol. 63(4) , 784-90, (2003) We describe a new molecular mechanism of cell death by excitotoxicity mediated through nuclear transcription factor kappa B (NF kappa B) in rat embryonic cultures of dopaminergic neurons. Treatment of... |
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Enhancement of CYP3A4 activity in Hep G2 cells by lentiviral transfection of hepatocyte nuclear factor-1 alpha.
PLoS ONE 9(4) , e94885, (2014) Human hepatoma cell lines are commonly used as alternatives to primary hepatocytes for the study of drug metabolism in vitro. However, the phase I cytochrome P450 (CYP) enzyme activities in these cell... |
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Interactions of endosulfan and methoxychlor involving CYP3A4 and CYP2B6 in human HepaRG cells.
Drug Metab. Dispos. 42(8) , 1235-40, (2014) Humans are usually exposed to several pesticides simultaneously; consequently, combined actions between pesticides themselves or between pesticides and other chemicals need to be addressed in the risk... |
| dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate |
| Dehydronifedipine |
| B 4759 |
| Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate |
| Nifedipine Impurity 1 |