Ethyl caffeate

Modify Date: 2025-08-26 18:52:22

Ethyl caffeate Structure
Ethyl caffeate structure
Common Name Ethyl caffeate
CAS Number 66648-50-8 Molecular Weight 208.211
Density 1.3±0.1 g/cm3 Boiling Point 377.0±32.0 °C at 760 mmHg
Molecular Formula C11H12O4 Melting Point N/A
MSDS USA Flash Point 148.4±18.6 °C

 Use of Ethyl caffeate


Ethyl trans-caffeate is the trans form of Ethyl Caffeate (HY-N6966). Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin[1].

 Names

Name ethyl 3,4-dihydroxycinnamate
Synonym More Synonyms

 Ethyl caffeate Biological Activity

Description Ethyl trans-caffeate is the trans form of Ethyl Caffeate (HY-N6966). Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin[1].
Related Catalog
References

[1]. Chiang YM, et al. Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin. Br J Pharmacol. 2005 Oct;146(3):352-63.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 377.0±32.0 °C at 760 mmHg
Molecular Formula C11H12O4
Molecular Weight 208.211
Flash Point 148.4±18.6 °C
Exact Mass 208.073563
PSA 66.76000
LogP 1.72
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.612
Storage condition 2-8℃

 Safety Information

Hazard Codes Xn
Risk Phrases R36/37/38
Safety Phrases S26-S36

 Synonyms

Ethyl caffeate
MFCD00045754
caffeic acid ethyl ester
2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, ethyl ester
ethyl caffeoate
Ethyl 3-(3,4-dihydroxyphenyl)acrylate
E-Caffeic acid ethyl ester
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