Ethyl 3-(3,4-dihydroxyphenyl)acrylate

Modify Date: 2025-08-22 09:05:40

Ethyl 3-(3,4-dihydroxyphenyl)acrylate structure	Common Name	Ethyl 3-(3,4-dihydroxyphenyl)acrylate
	CAS Number	102-37-4	Molecular Weight	208.211
	Density	1.3±0.1 g/cm3	Boiling Point	377.0±32.0 °C at 760 mmHg
	Molecular Formula	C₁₁H₁₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	148.4±18.6 °C

Use of Ethyl 3-(3,4-dihydroxyphenyl)acrylate

Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin[1].

Name	Ethyl 3-(3,4-dihydroxyphenyl)acrylate
Synonym	More Synonyms

Description	Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> COX
Target	NF-κB COX-2
In Vitro	Ethyl Caffeate markedly suppresses the lipopolysaccharide (LPS)-induced nitric oxide (NO) production with IC50 of 5.5 μg/ml[1].
References	[1]. Chiang YM, et al. Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin. Br J Pharmacol. 2005 Oct;146(3):352-63.

Density	1.3±0.1 g/cm3
Boiling Point	377.0±32.0 °C at 760 mmHg
Molecular Formula	C₁₁H₁₂O₄
Molecular Weight	208.211
Flash Point	148.4±18.6 °C
Exact Mass	208.073563
PSA	66.76000
LogP	1.72
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.612
Storage condition	2-8°C

Hazard Codes	Xi
HS Code	2918290000

HS Code	2918290000
Summary	HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%