(E/Z)-Polydatin

Modify Date: 2025-08-21 14:42:57

(E/Z)-Polydatin Structure
(E/Z)-Polydatin structure
Common Name (E/Z)-Polydatin
CAS Number 65914-17-2 Molecular Weight 407.39100
Density 1.521 g/cm3 Boiling Point 707.7ºC at 760 mmHg
Molecular Formula C20H22O8 Melting Point 223-226 °C(lit.)
MSDS USA Flash Point 381.8ºC

 Use of (E/Z)-Polydatin


(E/Z)-Polydatin ((E/Z)-Piceid) is a monocrystalline compound originally isolated from the root and rhizome of Polygonum cuspidatum. (E/Z)-Polydatin has anti-platelet aggregation, anti-oxidative action of low-density lipoprotein (LDL), cardioprotective activity, anti-inflammatory and immune-regulating functions[1].

 Names

Name (2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
Synonym More Synonyms

 (E/Z)-Polydatin Biological Activity

Description (E/Z)-Polydatin ((E/Z)-Piceid) is a monocrystalline compound originally isolated from the root and rhizome of Polygonum cuspidatum. (E/Z)-Polydatin has anti-platelet aggregation, anti-oxidative action of low-density lipoprotein (LDL), cardioprotective activity, anti-inflammatory and immune-regulating functions[1].
Related Catalog
References

[1]. Du QH, et al. Polydatin: a review of pharmacology and pharmacokinetics. Pharm Biol. 2013 Nov;51(11):1347-54.

 Chemical & Physical Properties

Density 1.521 g/cm3
Boiling Point 707.7ºC at 760 mmHg
Melting Point 223-226 °C(lit.)
Molecular Formula C20H22O8
Molecular Weight 407.39100
Flash Point 381.8ºC
Exact Mass 407.13400
PSA 160.07000
LogP 0.49640

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles30

More Articles
Protective effect of polydatin against burn-induced lung injury in rats.

Respir. Care 59(9) , 1412-21, (2014)

Polydatin (PD) has anti-inflammatory and anti-apoptotic effects in ischemic-reperfusion injury. Moreover, inflammatory responses and apoptosis play a role in the development of burn-induced lung injur...

Nephroprotective Effects of Polydatin against Ischemia/Reperfusion Injury: A Role for the PI3K/Akt Signal Pathway.

Oxid. Med. Cell. Longev. 2015 , 362158, (2015)

Oxidative stress and inflammation are involved in the pathogenesis in renal ischemia/reperfusion (I/R) injury. It has been demonstrated that polydatin processed the antioxidative, anti-inflammatory, a...

Pre-column incubation followed by fast liquid chromatography analysis for rapid screening of natural methylglyoxal scavengers directly from herbal medicines: case study of Polygonum cuspidatum.

J. Chromatogr. A. 1286 , 102-10, (2013)

Methylglyoxal (MGO), a very reactive metabolite of glucose, plays a pivotal role in the pathogenesis of several chronic diseases associated with diabetes, and it has been validated as an attractive ta...

 Synonyms

3,4,5-Tsg
trans-polydatin
MFCD00210592
(E)-Polydatin
Trans-Piceid
Giant knotweed Extract
Piceid
Reservatrol-3-β-mono-D-glucoside
Polydatin
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