1-Methoxyphaseollidin

Modify Date: 2025-08-23 13:20:49

1-Methoxyphaseollidin Structure
1-Methoxyphaseollidin structure
 Common Name 1-Methoxyphaseollidin
CAS Number 65428-13-9 Molecular Weight 354.39638
Density 1.3±0.1 g/cm3 Boiling Point 521.7±50.0 °C at 760 mmHg
Molecular Formula C21H22O5 Melting Point N/A
MSDS N/A Flash Point 269.3±30.1 °C

 Use of 1-Methoxyphaseollidin


1-Methoxyphaseollidin, a flavonoid compound, is a lysoPAF acetyltransferase inhibitor, with an IC50 of 48 μM. 1-Methoxyphaseollidin exhibits anti-H.pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains[1][2][3].

 Names

Name 1-methoxyphaseollidin
Synonym More Synonyms

 1-Methoxyphaseollidin Biological Activity

Description 1-Methoxyphaseollidin, a flavonoid compound, is a lysoPAF acetyltransferase inhibitor, with an IC50 of 48 μM. 1-Methoxyphaseollidin exhibits anti-H.pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains[1][2][3].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Fukai T, et, al. Anti-Helicobacter pylori flavonoids from licorice extract. Life Sci. 2002 Aug 9;71(12):1449-63.

[2]. Nagumo S, et, al. Inhibition of lysoPAF acetyltransferase activity by components of licorice root. Biol Pharm Bull. 1999 Oct;22(10):1144-6.

[3]. Sinha SK, et, al. Potential Leads from Liquorice Against SARS-CoV-2 Main Protease using Molecular Docking Simulation Studies. Comb Chem High Throughput Screen. 2021;24(4):591-597.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 521.7±50.0 °C at 760 mmHg
Molecular Formula C21H22O5
Molecular Weight 354.39638
Flash Point 269.3±30.1 °C
Exact Mass 354.146729
LogP 4.32
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.621
Storage condition 2-8℃

 Safety Information

Hazard Codes Xi

 Synonyms

EINECS 2017-001-1
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