SPCK
SPCK structure
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Common Name | SPCK | ||
|---|---|---|---|---|
| CAS Number | 65144-34-5 | Molecular Weight | 502.98900 | |
| Density | 1.234g/cm3 | Boiling Point | 809.4ºC at 760 mmHg | |
| Molecular Formula | C22H35ClN4O7 | Melting Point | 159-161ºC | |
| MSDS | USA | Flash Point | 443.3ºC | |
Use of SPCKMeOSuc-AAPV-CMK (Elastase Inhibitor III) is an elastase inhibitor. MeOSuc-AAPV-CMK also inhibits cathepsin G and proteinase 3.MeOSuc-AAPV-CMK blocks the cleavage of adiponectin by leukocyte elastase[1]. |
| Name | methoxysuccinyl-Ala-Ala-Pro-Val chloromethyl ketone |
|---|---|
| Synonym | More Synonyms |
| Description | MeOSuc-AAPV-CMK (Elastase Inhibitor III) is an elastase inhibitor. MeOSuc-AAPV-CMK also inhibits cathepsin G and proteinase 3.MeOSuc-AAPV-CMK blocks the cleavage of adiponectin by leukocyte elastase[1]. |
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| Related Catalog | |
| References |
| Density | 1.234g/cm3 |
|---|---|
| Boiling Point | 809.4ºC at 760 mmHg |
| Melting Point | 159-161ºC |
| Molecular Formula | C22H35ClN4O7 |
| Molecular Weight | 502.98900 |
| Flash Point | 443.3ºC |
| Exact Mass | 502.21900 |
| PSA | 150.98000 |
| LogP | 0.99930 |
| Index of Refraction | 1.513 |
| Storage condition | 20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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Comparison of the effects of methoxysuccinyl-Ala-Ala-Pro-Val-chloromethyl ketone-inhibited neutrophil elastase with the effects of its naturally occurring mutationally inactivated homologue (HBP) on fibroblasts and monocytes in vitro.
APMIS 100(12) , 1073-80, (1992) The mature neutrophils in the circulation contain, besides the different proteases known for a long time, a recently discovered proteolytically inactive elastase homologue (HBP/CAP37/azurocidin). This... |
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Polymorphonuclear cells isolated from human peripheral blood cleave lipoprotein(a) and apolipoprotein(a) at multiple interkringle sites via the enzyme elastase. Generation of mini-Lp(a) particles and apo(a) fragments.
J. Biol. Chem. 272(17) , 11079-87, (1997) Incubation of polymorphonuclear cells (PMN), isolated from human peripheral blood, with either lipoprotein(a) (Lp(a)) or free apolipoprotein(a) (apo(a)), derived from the parent Lp(a), caused in both ... |
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In vitro proteolysis of human plasma low density lipoproteins by an elastase released from human blood polymorphonuclear cells.
J. Biol. Chem. 261(5) , 2057-63, (1986) In vitro incubation of human plasma low density lipoproteins (LDL) with human blood polymorphonuclear cells (PMN) for 1 h at 37 degrees C resulted in an increased (2-4-fold) release into the medium of... |
| methyl 4-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(3S)-1-chloro-4-methyl-2-oxopentan-3-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoate |
| MeOSuc-Ala-Ala-Pro-Val-CMK |
| Meosuc-aapv-cmk |
| Methoxy-suc-ala-ala-pro-val-chloromethyl ketone |
| Msaapvck |
| methoxysuccinyl-alanyl-alanyl-prolyl-valine chloromethyl ketone |
| Elastase Inhibitor,SPCK |
| MeOSuc-Ala-Ala-Pro-Val-chloromethylketone |
- GL Biochem (Shanghai) Ltd.
- China
- Product Name: MeOSuc-Ala-Ala-Pro-Val-chloromethylketone
- Price: $Inquiry/1g
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Jackie Yang
- Nanjing Peptide Biotech Ltd
- China
- Product Name: MeOSuc-Ala-Ala-Pro-Val-chloromethylketone
- Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
- Purity: 98.0%
- Stocking Period: 7 Day
- Contact: jom
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: MeOSuc-Ala-Ala-Pro-Val-chloromethylketone
- Price: $Inquiry/1kg
- Purity: 99.0%
- Stocking Period: 1 Day
- Contact: Vinnie
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