Isoforskolin structure
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Common Name | Isoforskolin | ||
|---|---|---|---|---|
| CAS Number | 64657-21-2 | Molecular Weight | 410.501 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 524.5±50.0 °C at 760 mmHg | |
| Molecular Formula | C22H34O7 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 173.6±23.6 °C | |
Use of IsoforskolinIsoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis[1]. |
| Name | Coleonol B |
|---|---|
| Synonym | More Synonyms |
| Description | Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis[1]. |
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| Related Catalog | |
| In Vitro | Isoforskolin downregulates the transcription and expression of TNF-α and IL-6 induced by recombinant Borrelia burgdorferi basic membrane protein A (rBmpA)[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 524.5±50.0 °C at 760 mmHg |
| Molecular Formula | C22H34O7 |
| Molecular Weight | 410.501 |
| Flash Point | 173.6±23.6 °C |
| Exact Mass | 410.230438 |
| PSA | 113.29000 |
| LogP | 3.40 |
| Vapour Pressure | 0.0±3.1 mmHg at 25°C |
| Index of Refraction | 1.552 |
| Storage condition | −20°C |
| Precursor 0 | |
|---|---|
| DownStream 1 | |
| Isoforskolin |
| (3R,4aR,5S,6S,10S,10aR,10bS)-5,10,10b-Trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyldodecahydro-1H-benzo[f]chromen-6-yl acetate |
| 1H-Naphtho[2,1-b]pyran-1-one, 6-(acetyloxy)-3-ethenyldodecahydro-5,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, (3R,4aR,5S,6S,10S,10aR,10bS)- |
| 6-Acetyl-7-deacetylforskolin |