FF-MAS

Modify Date: 2025-09-10 17:18:00

FF-MAS Structure
FF-MAS structure
Common Name FF-MAS
CAS Number 64284-64-6 Molecular Weight 410.67500
Density 1g/cm3 Boiling Point 512.6ºC at 760 mmHg
Molecular Formula C29H46O Melting Point N/A
MSDS N/A Flash Point 221.9ºC

 Use of FF-MAS


FF-MAS is a potent meiotic maturation agonist. FF-MAS promotes meiotic maturation and preimplantation development of mouse oocytes maturing in vitro. FF-MAS promotes the completion of meiotic maturation to metaphase II (MII) and improves competence to complete the 2-cell stage to blastocyst transition[1][2].

 Names

Name 4,4-dimethyl-5α-cholesta-8,14,24-trien-3β-ol
Synonym More Synonyms

 FF-MAS Biological Activity

Description FF-MAS is a potent meiotic maturation agonist. FF-MAS promotes meiotic maturation and preimplantation development of mouse oocytes maturing in vitro. FF-MAS promotes the completion of meiotic maturation to metaphase II (MII) and improves competence to complete the 2-cell stage to blastocyst transition[1][2].
Related Catalog
In Vitro FF-MAS (1 µM;16-17 小时) 促进减数分裂成熟的完成和卵母细胞完成从 2 细胞阶段到囊胚转变的能力[1]。
References

[1]. Marín Bivens CL, et al. A synthetic analogue of meiosis-activating sterol (FF-MAS) is a potent agonist promoting meiotic maturation and preimplantation development of mouse oocytes maturing in vitro. Hum Reprod. 2004 Oct;19(10):2340-4.  

[2]. Thorsten Blume, et al. Two Syntheses of FF-MAS. Org. Lett. 2003, 5, 11, 1837-1839.

 Chemical & Physical Properties

Density 1g/cm3
Boiling Point 512.6ºC at 760 mmHg
Molecular Formula C29H46O
Molecular Weight 410.67500
Flash Point 221.9ºC
Exact Mass 410.35500
PSA 20.23000
LogP 8.00910
Index of Refraction 1.541
InChIKey LFQXEZVYNCBVDO-PBJLWWPKSA-N
SMILES CC(C)=CCCC(C)C1CC=C2C3=C(CCC21C)C1(C)CCC(O)C(C)(C)C1CC3

 Synthetic Route

 Synonyms

(3R,5S,10S,13S,17S)-4,4,10,13-tetramethyl-17-[(2R)-6-methylhept-5-en-2-yl]-1,2,3,5,6,7,11,12,16,17-decahydrocyclopenta[a]phenanthren-3-ol
(3β,5α)-4,4-Dimethylcholesta-8,14,24-trien-3-ol
4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
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