Neuropeptide FF Morphine Modulating Neuropeptide F-8-F-NH2

Modify Date: 2024-01-05 12:00:49

Neuropeptide FF Morphine Modulating Neuropeptide F-8-F-NH2 Structure
Neuropeptide FF Morphine Modulating Neuropeptide F-8-F-NH2 structure
Common Name Neuropeptide FF Morphine Modulating Neuropeptide F-8-F-NH2
CAS Number 99566-27-5 Molecular Weight 1081.27
Density 1.38 g/cm3 Boiling Point N/A
Molecular Formula C54H76N14O10 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of Neuropeptide FF Morphine Modulating Neuropeptide F-8-F-NH2


Neuropeptide FF (NPFF), an octapeptide belonging to the RF-amide family of peptides, interacts with two distinct G-protein-coupled receptors, NPFF(1) and NPFF(2) and has wide variety of physiological functions in the brain including central cardiovascular and neuroendocrine regulation[1][2].

 Names

Name Neuropeptide FF
Synonym More Synonyms

  Biological Activity

Description Neuropeptide FF (NPFF), an octapeptide belonging to the RF-amide family of peptides, interacts with two distinct G-protein-coupled receptors, NPFF(1) and NPFF(2) and has wide variety of physiological functions in the brain including central cardiovascular and neuroendocrine regulation[1][2].
Related Catalog
References

[1]. Mankus JV, et al. Nonpeptide ligands of neuropeptide FF: current status and structural insights. Future Med Chem. 2012 Jun;4(9):1085-92.

[2]. Jhamandas JH, et al. Role of neuropeptide FF in central cardiovascular and neuroendocrine regulation. Front Endocrinol (Lausanne). 2013 Feb 7;4:8.

 Chemical & Physical Properties

Density 1.38 g/cm3
Molecular Formula C54H76N14O10
Molecular Weight 1081.27
Exact Mass 1080.59000
PSA 412.10000
LogP 4.54270
Index of Refraction 1.656
Storage condition −20°C
Water Solubility Soluble to 0.50 mg/ml in water.

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles28

More Articles
The anti-inflammatory potential of neuropeptide FF in vitro and in vivo.

Peptides 47 , 124-32, (2013)

Neuropeptide FF (NPFF) has many functions in regulating various biological processes. However, little attention has been focused on the anti-inflammatory effect of this peptide. In the present study, ...

Intracerebroventricular administration of 26RFa produces an analgesic effect in the rat formalin test.

Peptides 30(9) , 1683-8, (2009)

GPR103 is one of the orphan G protein-coupled receptors. Recently, an endogenous ligand for GPR103, 26RFa, was identified. Many 26RFa binding sites have been observed in various nuclei of the brain in...

Pressor and tachycardic responses to intrathecal administration of neuropeptide FF in anesthetized rats.

Peptides 31(4) , 683-8, (2010)

Neuropeptide FF (NPFF) belongs to a neuropeptide family including two precursors (pro-NPFF(A) and pro-NPFF(B)) and two receptors (NPFF(1) and NPFF(2)). NPFF and NPFF receptor mRNAs have been reported ...

 Synonyms

H-PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE-NH2
ninamide
NPFF
PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE AMIDE
F-8-F-NH2
PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE-NH2
MFCD00076704
F-8-F-NH2,NPFF,F-8-F-aMide
TC Mps1 12
Neuropeptide FF Morphine Modulating Neuropeptide F-8-F-NH2
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