IMB-301

Modify Date: 2025-08-25 11:43:21

IMB-301 Structure
IMB-301 structure
Common Name IMB-301
CAS Number 64009-84-3 Molecular Weight 379.25500
Density 1.27g/cm3 Boiling Point 548.1ºC at 760mmHg
Molecular Formula C19H17Cl2FN2O Melting Point N/A
MSDS N/A Flash Point 285.3ºC

 Use of IMB-301


IMB-301 is a HIV-1 auxilins Vif degradation hA3G antagonist. IMB-301 inhibits hA3G-Vif interactions to inhibit Vif degradations hA3G. IMB-301 has anti-HIV-1 activity[1].

 Names

Name 1-[2-(2,4-dichlorophenyl)-4-(4-fluorophenoxy)butyl]imidazole
Synonym More Synonyms

 IMB-301 Biological Activity

Description IMB-301 is a HIV-1 auxilins Vif degradation hA3G antagonist. IMB-301 inhibits hA3G-Vif interactions to inhibit Vif degradations hA3G. IMB-301 has anti-HIV-1 activity[1].
Related Catalog
In Vitro IMB-301 can effectively inhibit the combination of Vif and hA3G[1]. IMB 301 can be by inhibiting Vif to inhibit Vif degradations hA3G with hA3G binding specificities[1].
References

[1]. Zhou, Jinming, et al. Applications of the IMB-301 in antiviral drugs is prepared. CN108261413A.

 Chemical & Physical Properties

Density 1.27g/cm3
Boiling Point 548.1ºC at 760mmHg
Molecular Formula C19H17Cl2FN2O
Molecular Weight 379.25500
Flash Point 285.3ºC
Exact Mass 378.07000
PSA 27.05000
LogP 5.58190
Index of Refraction 1.589
InChIKey FHKXBOJPHOEMQO-UHFFFAOYSA-N
SMILES Fc1ccc(OCCC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1

 Safety Information

Hazard Codes Xi

 Synonyms

3-(2,4-Dichlorophenyl)-4-(1H-imidazol-1-yl)butyl 4-fluorophenyl ether
1H-Imidazole,1-[2-(2,4-dichlorophenyl)-4-(4-fluorophenoxy)butyl]
IMB-301
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