64009-84-3
64009-84-3 structure
- Name: IMB-301
- Chemical Name: 1-[2-(2,4-dichlorophenyl)-4-(4-fluorophenoxy)butyl]imidazole
- CAS Number: 64009-84-3
- Molecular Formula: C19H17Cl2FN2O
- Molecular Weight: 379.25500
- Catalog: Signaling Pathways Anti-infection HIV
- Create Date: 2017-11-22 07:03:59
- Modify Date: 2025-08-25 11:43:21
-
IMB-301 is a HIV-1 auxilins Vif degradation hA3G antagonist. IMB-301 inhibits hA3G-Vif interactions to inhibit Vif degradations hA3G. IMB-301 has anti-HIV-1 activity[1].
| Name | 1-[2-(2,4-dichlorophenyl)-4-(4-fluorophenoxy)butyl]imidazole |
|---|---|
| Synonyms |
3-(2,4-Dichlorophenyl)-4-(1H-imidazol-1-yl)butyl 4-fluorophenyl ether
1H-Imidazole,1-[2-(2,4-dichlorophenyl)-4-(4-fluorophenoxy)butyl] IMB-301 |
| Description | IMB-301 is a HIV-1 auxilins Vif degradation hA3G antagonist. IMB-301 inhibits hA3G-Vif interactions to inhibit Vif degradations hA3G. IMB-301 has anti-HIV-1 activity[1]. |
|---|---|
| Related Catalog | |
| In Vitro | IMB-301 can effectively inhibit the combination of Vif and hA3G[1]. IMB 301 can be by inhibiting Vif to inhibit Vif degradations hA3G with hA3G binding specificities[1]. |
| References |
[1]. Zhou, Jinming, et al. Applications of the IMB-301 in antiviral drugs is prepared. CN108261413A. |
| Density | 1.27g/cm3 |
|---|---|
| Boiling Point | 548.1ºC at 760mmHg |
| Molecular Formula | C19H17Cl2FN2O |
| Molecular Weight | 379.25500 |
| Flash Point | 285.3ºC |
| Exact Mass | 378.07000 |
| PSA | 27.05000 |
| LogP | 5.58190 |
| Index of Refraction | 1.589 |
| Hazard Codes | Xi |
|---|