DL-AP4
Modify Date: 2025-08-26 00:00:28
DL-AP4 structure
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Common Name | DL-AP4 | ||
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| CAS Number | 6323-99-5 | Molecular Weight | 183.10000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C4H10NO5P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DL-AP4DL-AP4 (2-Amino-4-phosphonobutyric acid) is a glutamate antagonist. DL-AP4 behaves as a competitive inhibitor of glutamate binding with an apparent Kd of 66 μM. DL-AP4 can be used for the research of central nervous system and visual system[1][2][3]. |
| Name | 2-amino-4-phosphonobutanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | DL-AP4 (2-Amino-4-phosphonobutyric acid) is a glutamate antagonist. DL-AP4 behaves as a competitive inhibitor of glutamate binding with an apparent Kd of 66 μM. DL-AP4 can be used for the research of central nervous system and visual system[1][2][3]. |
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| Related Catalog | |
| Target |
Glutamate[1] |
| In Vitro | DL-AP4 (500 μM) reduces the tonic inward current by closing ion channels at holding potentials of -33 mV in isolated rod bipolar cells[1]. DL-AP4 (0.1 M; 1h) antagonizes the excitatory action of glutamate applied iontophoretically to receptors present in the locust muscle membrane[2]. DL-AP4 (compound 2) antagonizes excitatory synapses in the lateral perforant path of the rat hippocampal slice with an apparent Kd of 2.5 μM[3]. |
| References |
| Molecular Formula | C4H10NO5P |
|---|---|
| Molecular Weight | 183.10000 |
| Exact Mass | 183.03000 |
| PSA | 130.66000 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| HS Code | 2931900090 |
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| Precursor 0 | |
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| DownStream 3 | |
CAS#:995-32-4
CAS#:93960-22-6
CAS#:66508-32-5| HS Code | 2931900090 |
|---|---|
| Summary | 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0% |
| [3H]-(+/-)-AP 4 |
| DL-2-amino-4-phosphonobutyric acid |
| DL-2-AMINO-4-(DIHYDROXYPHOSPHINYL)BUTANOIC ACID |
| 2-amino-4-phosphonobutyric acid |
| DL-AP4 |