Methyl (2E)-3-(2,5-dihydroxyphenyl)acrylate
Methyl (2E)-3-(2,5-dihydroxyphenyl)acrylate structure
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Common Name | Methyl (2E)-3-(2,5-dihydroxyphenyl)acrylate | ||
|---|---|---|---|---|
| CAS Number | 63177-57-1 | Molecular Weight | 194.184 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 400.7±35.0 °C at 760 mmHg | |
| Molecular Formula | C10H10O4 | Melting Point | 178-180°C | |
| MSDS | Chinese USA | Flash Point | 163.3±19.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of Methyl (2E)-3-(2,5-dihydroxyphenyl)acrylateMethyl 2,5-dihydroxycinnamate is an erbstatin analog and a stable, potent inhibitor of EGFR kinase activity[1]. |
| Name | Methyl 2,5-Dihydroxycinnamate |
|---|---|
| Synonym | More Synonyms |
| Description | Methyl 2,5-dihydroxycinnamate is an erbstatin analog and a stable, potent inhibitor of EGFR kinase activity[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 400.7±35.0 °C at 760 mmHg |
| Melting Point | 178-180°C |
| Molecular Formula | C10H10O4 |
| Molecular Weight | 194.184 |
| Flash Point | 163.3±19.4 °C |
| Exact Mass | 194.057907 |
| PSA | 66.76000 |
| LogP | 1.51 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.629 |
| Storage condition | −20°C |
| Water Solubility | 0.1 M NaOH: soluble |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335 |
| Precautionary Statements | P301 + P312 + P330-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
| Hazard Codes | T: Toxic; |
| Risk Phrases | R23/24/25 |
| Safety Phrases | S22-S26-S36-S45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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Direct inhibition of the hexose transporter GLUT1 by tyrosine kinase inhibitors.
Biochemistry 40(3) , 777-90, (2001) The facilitative hexose transporter GLUT1 is a multifunctional protein that transports hexoses and dehydroascorbic acid, the oxidized form of vitamin C, and interacts with several molecules structural... |
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Mechanism of topoisomerase II inhibition by staurosporine and other protein kinase inhibitors.
J. Biol. Chem. 271(42) , 26418-23, (1996) Topoisomerase II is an essential enzyme for proliferation of eukaryotic cells. It is also a target for many antineoplastic drugs that promote stabilization of covalent complexes between topoisomerase ... |
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Signal pathways that transduce growth factor-stimulated mitogenesis in bone cells.
Bone 23(1) , 17-26, (1998) This investigation examined which signal pathways are of relevance in growth factor-stimulated bone cell mitogenesis. Platelet-derived growth factor (PDGF) and insulin-like growth factor-II (IGF-II) w... |
| 2-Propenoic acid, 3-(2,5-dihydroxyphenyl)-, methyl ester, (2E)- |
| Methyl (2E)-3-(2,5-dihydroxyphenyl)acrylate |
| MFCD00132932 |
| methyl (E)-3-(2,5-dihydroxyphenyl)prop-2-enoate |