1,2-Diethoxyethane

Modify Date: 2025-08-21 06:00:51

1,2-Diethoxyethane structure	Common Name	1,2-Diethoxyethane
	CAS Number	629-14-1	Molecular Weight	118.17400
	Density	0.842 g/mL at 25 °C(lit.)	Boiling Point	121 °C(lit.)
	Molecular Formula	C₆H₁₄O₂	Melting Point	-74 °C
	MSDS	Chinese USA	Flash Point	69 °F
	Symbol	GHS02, GHS07, GHS08	Signal Word	Danger

Name	Ethylene glycol diethyl ether
Synonym	More Synonyms

Density	0.842 g/mL at 25 °C(lit.)
Boiling Point	121 °C(lit.)
Melting Point	-74 °C
Molecular Formula	C₆H₁₄O₂
Molecular Weight	118.17400
Flash Point	69 °F
Exact Mass	118.09900
PSA	18.46000
LogP	1.05940
Vapour Pressure	9.4 mm Hg ( 20 °C)
Index of Refraction	n20/D 1.3923(lit.)
Water Solubility	Slightly soluble

1,2-Diethoxyethane MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KI1225000

CHEMICAL NAME :: Ethane, 1,2-diethoxy-

CAS REGISTRY NUMBER :: 629-14-1

BEILSTEIN REFERENCE NO. :: 1732917

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C6-H14-O2

MOLECULAR WEIGHT :: 118.20

WISWESSER LINE NOTATION :: 2O2O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4390 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Gastrointestinal - other changes Kidney, Ureter, Bladder - other changes

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 23,259,1941

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8000 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,343,1949

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 2440 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Gastrointestinal - other changes Kidney, Ureter, Bladder - other changes

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 23,259,1941 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 23640 mg/kg

SEX/DURATION :: female 7-14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :: EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 57,141,1984

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 23640 mg/kg

SEX/DURATION :: female 6-13 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Effects on Newborn - live birth index (measured after birth) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

REFERENCE :: TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980- Volume(issue)/page/year: 7,29,1987

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 5000 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB88-134093

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 10 gm/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB88-134093

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1400 mg/kg

SEX/DURATION :: female 6-19 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 19,15,1992

Symbol	GHS02, GHS07, GHS08
Signal Word	Danger
Hazard Statements	H225-H319-H360Df
Supplemental HS	May form explosive peroxides.
Precautionary Statements	P201-P210-P305 + P351 + P338-P308 + P313
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant;
Risk Phrases	R10;R37/38;R41
Safety Phrases	S16-S26-S36
RIDADR	UN 1153 3/PG 2
WGK Germany	2
RTECS	KI1225000
Packaging Group	II
Hazard Class	3
HS Code	2942000000

Precursor 10
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CAS#:39114-77-7 1,1-bis-(2-etho... CAS#:628-34-2 2-Chloroethyl E...
DownStream 9
CAS#:22056-82-2 ETHOXYACETALDEHYDE CAS#:16484-86-9 1,2-Diethoxyethane CAS#:120188-10-5 (2R,3R,4S,6R)-3... CAS#:109-92-2 Ethoxyethene
CAS#:933-20-0 2-Amino-4,6-dic... CAS#:123-91-1 1,4-Dioxane CAS#:592-55-2 2-Bromoethoxyethane CAS#:524684-52-4 Prinaberel
CAS#:1577-55-5 9-Octadecene-1,...

HS Code	2942000000

From 1,2-dialkoxyalkanes to 1,4-dioxanes. A transformation mediated by NbCl(5)via multiple C-O bond cleavage at room temperature.

Chem. Commun. (Camb.) (31) , 3651-3, (2008)

The formation of 1,4-dioxanes and alkyl chlorides from the reactions of polyethers (dme, diglyme, 1,2-diethoxyethane, 1,2-dimethoxypropane) with NbCl(5) at room temperature is described; as far as dme...

[Effects of oxygenated fuels on emissions and carbon composition of fine particles from diesel engine].

Huan Jing Ke Xue 30(6) , 1561-6, (2009)

Acetal (1,1-diethoxyethane) is considered as an alternative to ethanol as bio-derived additive for diesel fuel, which is miscible in diesel fuel. Biodiesel can improve the oxygen content and flash poi...

The developmental toxicity of ethylene glycol diethyl ether in mice and rabbits.

Fundam. Appl. Toxicol. 19(1) , 15-25, (1992)

Timed-pregnant CD-1 outbred Albino Swiss mice and New Zealand White rabbits were dosed by gavage with ethylene glycol diethyl ether (EGdiEE) in distilled water during major organogenesis. Mice were do...

1,2-diethoxyethane

MFCD00009253

EINECS 211-076-1

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 1,2-Diethoxyethane
Price: Check
Purity: 99.5%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 1,2-Diethoxyethane
Price: ￥88.0/500ml
Purity: 98.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,2-Diethoxyethane
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: CAS No.629-14-1 Ethylene glycol diethyl ether
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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1,2-Diethoxyethane

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