Azide-C2-Azide

Modify Date: 2024-01-09 19:35:43

Azide-C2-Azide Structure
Azide-C2-Azide structure
Common Name Azide-C2-Azide
CAS Number 629-13-0 Molecular Weight 112.09300
Density N/A Boiling Point N/A
Molecular Formula C2H4N6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azide-C2-Azide


Azide-C2-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name 1,2-Diazidoethane
Synonym More Synonyms

 Azide-C2-Azide Biological Activity

Description Azide-C2-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Molecular Formula C2H4N6
Molecular Weight 112.09300
Exact Mass 112.05000
PSA 99.50000
LogP 0.51252

 Synthetic Route

~72%

Azide-C2-Azide Structure

Azide-C2-Azide

CAS#:629-13-0

Literature: Betzler, Franziska M.; Klapoetke, Thomas M.; Sproll, Stefan M. European Journal of Organic Chemistry, 2013 , # 3 p. 509 - 514

~73%

Azide-C2-Azide Structure

Azide-C2-Azide

CAS#:629-13-0

Literature: Vereshchagin, L. I.; Tikhonova, L. G.; Maksikova, A. V.; Serebryakova, E. S.; Proidakov, A. G.; Filippova, T. M. Journal of Organic Chemistry USSR (English Translation), 1980 , vol. 16, # 4 p. 641 - 648 Zhurnal Organicheskoi Khimii, 1980 , vol. 16, # 4 p. 730 - 738

 Synonyms

Aethylendiazid
Ethane,1,2-diazido
1,2-Diazido-aethan
1,2-diazido-ethane
1.2-Diazo-aethan
Aethylenazid