Nonanoic acid-d2

Modify Date: 2024-01-08 14:44:12

Nonanoic acid-d2 Structure
Nonanoic acid-d2 structure
Common Name Nonanoic acid-d2
CAS Number 62689-94-5 Molecular Weight 160.25000
Density N/A Boiling Point N/A
Molecular Formula C9H16D2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Nonanoic acid-d2


Nonanoic acid-d2 is the deuterium labeled Nonanoic acid[1]. Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2[2].

 Names

Name α,α-D2-nonanoic acid
Synonym More Synonyms

 Nonanoic acid-d2 Biological Activity

Description Nonanoic acid-d2 is the deuterium labeled Nonanoic acid[1]. Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Wang J, et al. Caprylic acid and nonanoic acid upregulate endogenous host defense peptides to enhance intestinal epithelial immunological barrier function via histone deacetylase inhibition.Int Immunopharmacol. 2018 Dec;65:303-311.  

 Chemical & Physical Properties

Molecular Formula C9H16D2O2
Molecular Weight 160.25000
Exact Mass 160.14300
PSA 37.30000
LogP 2.82160

 Synonyms

2,2-Dideutero-nonansaeure
2,2-dideuterio-nonanoic acid
nonanoic acid-αd2