62689-94-5

62689-94-5 structure

Name: Nonanoic acid-d2
Chemical Name: α,α-D2-nonanoic acid
CAS Number: 62689-94-5
Molecular Formula: C₉H₁₆D₂O₂
Molecular Weight: 160.25000
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-06-12 17:04:42
Modify Date: 2024-01-08 14:44:12
Nonanoic acid-d2 is the deuterium labeled Nonanoic acid[1]. Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2[2].

Name	α,α-D2-nonanoic acid
Synonyms	2,2-Dideutero-nonansaeure 2,2-dideuterio-nonanoic acid nonanoic acid-αd2

Description	Nonanoic acid-d2 is the deuterium labeled Nonanoic acid[1]. Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2[2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Wang J, et al. Caprylic acid and nonanoic acid upregulate endogenous host defense peptides to enhance intestinal epithelial immunological barrier function via histone deacetylase inhibition.Int Immunopharmacol. 2018 Dec;65:303-311.