4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine

Modify Date: 2024-01-13 19:43:42

4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine Structure
4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine structure
Common Name 4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine
CAS Number 623950-02-7 Molecular Weight 336.383
Density 1.2±0.1 g/cm3 Boiling Point 497.1±45.0 °C at 760 mmHg
Molecular Formula C17H24N2O5 Melting Point >210℃
MSDS N/A Flash Point 254.4±28.7 °C

 Use of 4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine


(S)-2-(tert-butoxycarbonylamino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid is a phenylalanine derivative[1].

 Names

Name (2S)-3-(4-carbamoyl-2,6-dimethylphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
Synonym More Synonyms

  Biological Activity

Description (S)-2-(tert-butoxycarbonylamino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid is a phenylalanine derivative[1].
Related Catalog
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-839.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 497.1±45.0 °C at 760 mmHg
Melting Point >210℃
Molecular Formula C17H24N2O5
Molecular Weight 336.383
Flash Point 254.4±28.7 °C
Exact Mass 336.168518
PSA 118.72000
LogP 2.41
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.549

 Safety Information

Hazard Codes Xi
HS Code 2924299090

 Synthetic Route

~94%

4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine Structure

4-(Aminocarbony...

CAS#:623950-02-7

Literature: Breslin, Henry J.; Cai, Chaozhong; He, Wei; Kavash, Robert W. Patent: US2005/203143 A1, 2005 ; Location in patent: Page/Page column 46 ; US 20050203143 A1

~%

4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine Structure

4-(Aminocarbony...

CAS#:623950-02-7

Literature: JANSSEN PHARMACEUTICA NV; FEIBUSH, Penina; ANZALONE, Luigi; VILLANI, Frank, J. Patent: WO2010/62590 A2, 2010 ; Location in patent: Page/Page column 31 ;

~%

4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine Structure

4-(Aminocarbony...

CAS#:623950-02-7

Literature: Cai, Chaozhong; Breslin, Henry J.; He, Wei Tetrahedron, 2005 , vol. 61, # 28 p. 6836 - 6838

~%

4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine Structure

4-(Aminocarbony...

CAS#:623950-02-7

Literature: Cai, Chaozhong; Breslin, Henry J.; He, Wei Tetrahedron, 2005 , vol. 61, # 28 p. 6836 - 6838

~%

4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine Structure

4-(Aminocarbony...

CAS#:623950-02-7

Literature: Cai, Chaozhong; Breslin, Henry J.; He, Wei Tetrahedron, 2005 , vol. 61, # 28 p. 6836 - 6838

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

L-Phenylalanine, 4-(aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-
4'-carbamoyl N-Boc-2',6'-dimethyl-L-phenylalanine
4-Carbamoyl-2,6-dimethyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanine
SC1127
(S)-2-tert-Butoxycarbonylamino-3-(4-carbamoyl-2,6-dimethylphenyl)-propionic Acid
(S)-2-(tert-butoxycarbonylamino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid
4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine
Eluxadoline Intermediate 2
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