Leucovorin Calcium Pentahydrate
Modify Date: 2024-01-03 10:17:45
Leucovorin Calcium Pentahydrate structure
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Common Name | Leucovorin Calcium Pentahydrate | ||
|---|---|---|---|---|
| CAS Number | 6035-45-6 | Molecular Weight | 601.58 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H31CaN7O12 | Melting Point | 240-250ºC | |
| MSDS | N/A | Flash Point | N/A | |
Use of Leucovorin Calcium PentahydrateFolinic Acid is a reduced folic acid, which is used in combination with other chemotherapy drugs.Target: Folate analogApproved: 2008Folinic acid (calcium salt pentahydrate) is the calcium salt form of folinic acid, which is one of the forms of folate found naturally in foods. Folate deficiency is believed to be the most common vitamin deficiency in the world due to food processing, food selection, and intestinal disorders. Folinic acid in the body can be converted into any of the other active forms of folate.Treatment with folinic acid calcium salt pentahydrate (CF) could cause improved development in the heart and vessels in MTX-treated embryos, which proved that MTX induced the malformations by inhibiting DHFR. The transcript levels of genes such as hand2, mef2a, mef2c, and flk-1 were reduced in MTX-treated embryos. Compared with the MTX-treated group, the transcript levels of hand2, mef2a, mef2c, and flk-1 were increased in the MTX + dhfr-gfp mRNA-injected group and in the MTX + CF group [1]. Folinic acid may also be useful in the treatment of acute methotrexate overdose. Different dosing protocols are used, but folinic acid should be re-dosed until the methotrexate level is less than 5 x 10-8 M [2]. |
| Name | Calcium folinatc |
|---|---|
| Synonym | More Synonyms |
| Description | Folinic Acid is a reduced folic acid, which is used in combination with other chemotherapy drugs.Target: Folate analogApproved: 2008Folinic acid (calcium salt pentahydrate) is the calcium salt form of folinic acid, which is one of the forms of folate found naturally in foods. Folate deficiency is believed to be the most common vitamin deficiency in the world due to food processing, food selection, and intestinal disorders. Folinic acid in the body can be converted into any of the other active forms of folate.Treatment with folinic acid calcium salt pentahydrate (CF) could cause improved development in the heart and vessels in MTX-treated embryos, which proved that MTX induced the malformations by inhibiting DHFR. The transcript levels of genes such as hand2, mef2a, mef2c, and flk-1 were reduced in MTX-treated embryos. Compared with the MTX-treated group, the transcript levels of hand2, mef2a, mef2c, and flk-1 were increased in the MTX + dhfr-gfp mRNA-injected group and in the MTX + CF group [1]. Folinic acid may also be useful in the treatment of acute methotrexate overdose. Different dosing protocols are used, but folinic acid should be re-dosed until the methotrexate level is less than 5 x 10-8 M [2]. |
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| Related Catalog | |
| References |
| Melting Point | 240-250ºC |
|---|---|
| Molecular Formula | C20H31CaN7O12 |
| Molecular Weight | 601.58 |
| PSA | 427.76000 |
| Storage condition | -20℃ |
| Hazard Codes | Xn: Harmful; |
|---|---|
| Risk Phrases | 36/37/38-42/43 |
| Safety Phrases | 26-36 |
| WGK Germany | 3 |
| HS Code | 2942000000 |
| Precursor 0 | |
|---|---|
| DownStream 1 | |
CAS#:58-05-9| HS Code | 2942000000 |
|---|
| Folaren |
| Foliben |
| 5-formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid calcium salt |
| FOLINIC ACID CALCIUM CELL CULTURE TESTED |
| Folinic acid calcium salt |
| Folidan |
| Leucovorin 30(R) |
| CALCIUM FOLINATE(FOLINIC ACID)(RG) |
| Calcium 2-amino-6-[(4-{[(1S)-1-carboxy-3-carboxylatopropyl]carbamoyl}phenyl)(methyl)amino]-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridine 2-amino-6-[{4-[(1-carboxy-3-carboxylatopropyl)carbamoyl]phenyl}(methyl)amino]-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridine (1:1:1) |
| (6S)-calcium folinate |
| Leucovorin Calcium |
| Leucovorin calcium pentahydrate |
| FOLINIC ACID(SEE CALCIUM FOLINATE) |
| Folinic acid (calcium salt pentahydrate) |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Leucovorin Calcium Pentahydrate
- Price: ￥548.0/100mg
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Folinic acid calcium salt pentahydrate
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: CALCIUM FOLINATE PENTAHYDRATE
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Calcium folinatc
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
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Price: ￥392/100mg
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