butyrin
Modify Date: 2024-01-02 10:40:21
butyrin structure
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Common Name | butyrin | ||
|---|---|---|---|---|
| CAS Number | 60-01-5 | Molecular Weight | 302.363 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 307.5±0.0 °C at 760 mmHg | |
| Molecular Formula | C15H26O6 | Melting Point | -75 °C | |
| MSDS | Chinese USA | Flash Point | 173.9±0.0 °C | |
Use of butyrinTributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into the cell in vivo. Tributyrin has potent antiproliferative, proapoptotic and differentiation-inducing effects[1]. |
| Name | tributyrin |
|---|---|
| Synonym | More Synonyms |
| Description | Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into the cell in vivo. Tributyrin has potent antiproliferative, proapoptotic and differentiation-inducing effects[1]. |
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| Related Catalog | |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 307.5±0.0 °C at 760 mmHg |
| Melting Point | -75 °C |
| Molecular Formula | C15H26O6 |
| Molecular Weight | 302.363 |
| Flash Point | 173.9±0.0 °C |
| Exact Mass | 302.172943 |
| PSA | 78.90000 |
| LogP | 2.95 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.448 |
| Storage condition | Store at RT. |
| Stability | Stable. Incompatible with strong oxidizing agents. |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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~92%
butyrin CAS#:60-01-5 |
| Literature: Prager, Rolf H.; Yurui, Zhang Australian Journal of Chemistry, 1989 , vol. 42, # 6 p. 1003 - 1005 |
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~95%
butyrin CAS#:60-01-5 |
| Literature: Akthelia Pharmaceuticals Patent: US2011/118217 A1, 2011 ; |
|
~%
butyrin CAS#:60-01-5 |
| Literature: Nudelman, Abraham; Ruse, Margaretta; Aviram, Adina; Rabizadeh, Ester; Shaklai, Matityahu; et al. Journal of Medicinal Chemistry, 1992 , vol. 35, # 4 p. 687 - 694 |
|
~%
butyrin CAS#:60-01-5 |
| Literature: Newman; Trikojus; Harker Journal and Proceedings of the Royal Society of New South Wales, vol. 59, p. 296 Chem. Zentralbl., 1927 , vol. 98, # II p. 802 |
|
~%
butyrin CAS#:60-01-5 |
| Literature: Partheil; v.Velsen Archiv der Pharmazie (Weinheim, Germany), 1900 , vol. 238, p. 267 |
|
~%
butyrin CAS#:60-01-5 |
| Literature: Newman; Trikojus; Harker Journal and Proceedings of the Royal Society of New South Wales, vol. 59, p. 298 Chem. Zentralbl., 1927 , vol. 98, # II p. 802 |
|
~%
butyrin CAS#:60-01-5 |
| Literature: Guth Z.B., 1903 , vol. 44, p. 95 |
| Precursor 7 | |
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| DownStream 9 | |
CAS#:557-25-5
CAS#:30403-46-4
CAS#:17364-00-0
CAS#:623-42-7
CAS#:56149-03-2
CAS#:555-43-1
CAS#:66411-63-0
CAS#:139665-43-3| HS Code | 2915900090 |
|---|---|
| Summary | 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0% |
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Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin.
AAPS J. 16(4) , 875-83, (2014) The effect of food intake on the release and degradation of peptide drugs from solid lipid particles is unknown and was therefore investigated in vitro using different fed state media in a lipolysis m... |
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Biochemistry of lipolytic enzymes secreted by Penicillium solitum and Cladosporium cladosporioides.
Biosci. Biotechnol. Biochem. 78(2) , 245-54, (2014) Two distinct extracellular lipases were obtained from Penicillium solitum 194A, isolated from domestic compost, and Cladosporium cladosporioides 194B, isolated from dairy wastewater. These alkaline en... |
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Candida rugosa lipase immobilization on hydrophilic charged gold nanoparticles as promising biocatalysts: Activity and stability investigations.
Colloids Surf. B Biointerfaces 131 , 93-101, (2015) In this work, a simple and versatile methodology to obtain two different bioconjugated systems has been developed by the immobilization of Candida rugosa lipase (CRL) on hydrophilic gold nanoparticles... |
| Tributyrinine |
| MFCD00009392 |
| 1,2,3-Propanetriyl tributanoate |
| Butanoic acid, 1,2,3-propanetriyl ester |
| Propane-1,2,3-triyl tributanoate |
| Tributyroin |
| glyceryl tributyrate |
| Tributin |
| Butyryl triglyceride |
| Glycerol tributyrate |
| 2,3-di(butanoyloxy)propyl butanoate |
| EINECS 200-451-5 |
| glycerol tributanoate |
| 1,2,3-Tributyrylglycerol |
| Butanoic acid,1,2,3-propanetriyl ester |
| butyrin |
| TRIBUTYRIN |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: butyrin
- Price: ￥68.0/25ml ￥228.0/100ml
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: NSC-661583
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Stocking Period: 1 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Glyceryl tributyrate
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Tributyrin
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Butanoic acid,1,2,3-propanetriyl ester
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
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Price: ￥500/25 mg
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