Eniluracil
Modify Date: 2025-08-24 21:53:54
Eniluracil structure
|
Common Name | Eniluracil | ||
|---|---|---|---|---|
| CAS Number | 59989-18-3 | Molecular Weight | 136.10800 | |
| Density | 1.39g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C6H4N2O2 | Melting Point | 320 °C(dec.) | |
| MSDS | N/A | Flash Point | N/A | |
Use of EniluracilEniluracil (5-Ethynyluracil), a uracil analogue and a mechanism-based irreversible inhibitor of dihydropyrimidine dehydrogenase (DPD), increases the oral bioavailability of 5-fluorouracil (5-FU) to 100%, facilitating uniform absorption and predictable toxicity[1]. |
| Name | 5-ethynyl-1H-pyrimidine-2,4-dione |
|---|---|
| Synonym | More Synonyms |
| Description | Eniluracil (5-Ethynyluracil), a uracil analogue and a mechanism-based irreversible inhibitor of dihydropyrimidine dehydrogenase (DPD), increases the oral bioavailability of 5-fluorouracil (5-FU) to 100%, facilitating uniform absorption and predictable toxicity[1]. |
|---|---|
| Related Catalog | |
| Target |
Dihydropyrimidine dehydrogenase[1] |
| References |
| Density | 1.39g/cm3 |
|---|---|
| Melting Point | 320 °C(dec.) |
| Molecular Formula | C6H4N2O2 |
| Molecular Weight | 136.10800 |
| Exact Mass | 136.02700 |
| PSA | 65.72000 |
| Index of Refraction | 1.589 |
| InChIKey | JOZGNYDSEBIJDH-UHFFFAOYSA-N |
| SMILES | C#Cc1c[nH]c(=O)[nH]c1=O |
|
~97%
Eniluracil CAS#:59989-18-3 |
| Literature: Cooke, Jason W. B.; Bright, Robert; Coleman, Mark J.; Jenkins, Kevin P. Organic Process Research and Development, 2001 , vol. 5, # 4 p. 383 - 386 |
|
~72%
Eniluracil CAS#:59989-18-3 |
| Literature: Kundu, Nitya G.; Das, Biswajit; Majumdar, Anjali Synthesis, 1990 , # 3 p. 243 - 245 |
|
~%
Eniluracil CAS#:59989-18-3 |
| Literature: Journal of Heterocyclic Chemistry, , vol. 19, # 3 p. 463 - 464 |
|
~%
Eniluracil CAS#:59989-18-3 |
| Literature: Journal of Heterocyclic Chemistry, , vol. 19, # 3 p. 463 - 464 |
CAS#:61135-33-9![FURO[2,3-D]PYRIMIDIN-2(3H)-ONE structure](https://image.chemsrc.com/caspic/457/62785-91-5.png)
CAS#:62785-91-5| ethynyluracil |
| 5-ETHYNYLURACIL |
| Compound 776C |
| Eniluracil |
| ethynyluracyl |
| GW776C85 |
| 776C85 |