1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one

Modify Date: 2024-01-03 11:43:49

1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one Structure
1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one structure
 Common Name 1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one
CAS Number 59892-36-3 Molecular Weight 272.21
Density N/A Boiling Point N/A
Molecular Formula C10H12N2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one


1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one
Synonym More Synonyms

  Biological Activity

Description 1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C10H12N2O7
Molecular Weight 272.21
Exact Mass 272.06400
PSA 137.74000

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-nitropyridin-2-one
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Chemsrc provides CAS#:59892-36-3 MSDS, density, melting point, boiling point, structure, etc. Its name is 1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one>> amp version: 1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one

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