59892-36-3

59892-36-3 structure

Name: 1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one
Chemical Name: 1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one
CAS Number: 59892-36-3
Molecular Formula: C₁₀H₁₂N₂O₇
Molecular Weight: 272.21
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2017-12-17 20:44:40
Modify Date: 2024-01-03 11:43:49
1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one
Synonyms	1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-nitropyridin-2-one

Description	1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Precursor 0
DownStream 1
59892-40-9