Pancreatic polypeptide

Modify Date: 2024-02-02 19:37:45

Pancreatic polypeptide Structure
Pancreatic polypeptide structure
Common Name Pancreatic polypeptide
CAS Number 59763-91-6 Molecular Weight 444.52000
Density 1.272g/cm3 Boiling Point 612.8ºC at 760 mmHg
Molecular Formula C31H24O3 Melting Point 154-155ºC
MSDS N/A Flash Point 204.3ºC

 Use of Pancreatic polypeptide


Pancreatic polypeptide is a peptide secreted by the endocrine PP cells of the pancreas that regulates pancreatic secretory activity and also affects hepatic glycogen stores and gastrointestinal secretion[1].

 Names

Name 3-[3-(4-Biphenylyl)-1,2,3,4-tetrahydro-1-naphthalenyl]-2-hydroxy- 4H-chromen-4-one

 Pancreatic polypeptide Biological Activity

Description Pancreatic polypeptide is a peptide secreted by the endocrine PP cells of the pancreas that regulates pancreatic secretory activity and also affects hepatic glycogen stores and gastrointestinal secretion[1].
Related Catalog
In Vitro Pancreatic polypeptid (PP) (0.1 μM, 48 h) 导致 mHippo E18 细胞的生长抑素分泌显着减少[1]。
In Vivo Pancreatic polypeptid (PP) (1 μM, Hippocampal injection, 0.2 μL/min followed by 3 min) 可以刺激小鼠脑中含生长抑素细胞中神经元激活标记物 c-Fos 的表达,表明其可以激活小鼠海马体中含生长抑素的细胞[1]。
References

[1]. Wook Kim, et al. Pancreatic polypeptide inhibits somatostatin secretion. FEBS Lett. 2014 Aug 25;588(17):3233-9.  

 Chemical & Physical Properties

Density 1.272g/cm3
Boiling Point 612.8ºC at 760 mmHg
Melting Point 154-155ºC
Molecular Formula C31H24O3
Molecular Weight 444.52000
Flash Point 204.3ºC
Exact Mass 444.17300
PSA 50.44000
LogP 7.02750