Lorcainide

Modify Date: 2024-01-03 07:43:09

Lorcainide Structure
Lorcainide structure
Common Name Lorcainide
CAS Number 59729-31-6 Molecular Weight 370.91600
Density 1.161g/cm3 Boiling Point 503ºC at 760 mmHg
Molecular Formula C22H27ClN2O Melting Point N/A
MSDS N/A Flash Point 258ºC

 Names

Name N-(4-chlorophenyl)-2-phenyl-N-(1-propan-2-ylpiperidin-4-yl)acetamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.161g/cm3
Boiling Point 503ºC at 760 mmHg
Molecular Formula C22H27ClN2O
Molecular Weight 370.91600
Flash Point 258ºC
Exact Mass 370.18100
PSA 23.55000
LogP 4.72640
Index of Refraction 1.594
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CY1483600
CHEMICAL NAME :
Benzeneacetamide, N-(4-chlorophenyl)-N-(1-(1-methylethyl)-4-piperidinyl )-
CAS REGISTRY NUMBER :
59729-31-6
BEILSTEIN REFERENCE NO. :
0497568
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C22-H27-Cl-N2-O
MOLECULAR WEIGHT :
370.96

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - coma Cardiac - pulse rate
REFERENCE :
JTCTDW Journal of Toxicology, Clinical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.19- 1982- Volume(issue)/page/year: 33,157,1995
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
395 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RMISDU International Congress and Symposium Series - Royal Society of Medicine Services Limited. (Royal Society of Medicine Services Ltd., 7E. 60th St., New York, NY 10022) No.1- 1978- Volume(issue)/page/year: 49,23,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
18600 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RMISDU International Congress and Symposium Series - Royal Society of Medicine Services Limited. (Royal Society of Medicine Services Ltd., 7E. 60th St., New York, NY 10022) No.1- 1978- Volume(issue)/page/year: 49,23,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
483 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RMISDU International Congress and Symposium Series - Royal Society of Medicine Services Limited. (Royal Society of Medicine Services Ltd., 7E. 60th St., New York, NY 10022) No.1- 1978- Volume(issue)/page/year: 49,23,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
18800 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RMISDU International Congress and Symposium Series - Royal Society of Medicine Services Limited. (Royal Society of Medicine Services Ltd., 7E. 60th St., New York, NY 10022) No.1- 1978- Volume(issue)/page/year: 49,23,1981

 Safety Information

Hazard Codes Xn
Safety Phrases 26-36/37

 Synonyms

Lorcainidum [INN-Latin]
Benzeneacetamide,N-(4-chlorophenyl)-N-[1-(1-methylethyl)-4-piperidinyl]
N-(4-chloro-phenyl)-N-(1-isopropyl-piperidin-4-yl)-2-phenyl-acetamide
LORCAINIDE
N-(4-chlorophenyl)-N-[1-(1-methylethyl)-4-piperidinyl]benzeneacetamide
Lorcainida [INN-Spanish]
4'-Chloro-N-(1-isopropyl-4-piperidyl)-2-phenylacetanilide
Lorcainide [INN:BAN]
lorcainid
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